1430415-03-4

Basic information

• Product Name: 4-(2-methylcyclohexyloxy)-6-phenethyl pyridin-2(1H)-one
• Synonyms: 4-(2-methylcyclohexyloxy)-6-phenethyl pyridin-2(1H)-one
• CAS NO: 1430415-03-4
• Molecular Weight: 311.424
• Mol File: 1430415-03-4.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 4-(2-methylcyclohexyloxy)-6-phenethyl pyridin-2(1H)-one(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(2-methylcyclohexyloxy)-6-phenethyl pyridin-2(1H)-one(1430415-03-4)
• EPA Substance Registry System: 4-(2-methylcyclohexyloxy)-6-phenethyl pyridin-2(1H)-one(1430415-03-4)

Safety Data

• Hazardous Substances Data: 1430415-03-4(Hazardous Substances Data)

Upstream product

• 583-59-5 2-Methylcyclohexanol 
• 17071-29-3 ethyl 3-oxo-5-phenylpentanoate 
• 1430415-02-3 ethyl 2-(benzyloxy)-4-(2-methylcyclohexyloxy)-6-phenethyl nicotinate 
• 1282619-52-6 ethyl 2-(benzyloxy)-4-hydroxy-6-phenethylnicotinate 
• 1282619-44-6 ethyl 4-hydroxy-2-oxo-6-phenethyl-1,2-dihydropyridine-3-carboxylate 
• 855737-23-4 ethyl 3-amino-5-phenylpent-2-enoate 
• 645-45-4 hydrocinnamic acid chloride 

Relevant articles and documents

A stereo configuration-activity study of 3-iodo-4-(2-methylcyclohexyloxy)-6-phenethylpyridin-2(2H)-ones as potency inhibitors of HIV-1 variants

3-Iodo-4-(2′-methylcyclohexyloxy)-6-phenethylpyridin-2(1H)-ones, as effective non-nucleoside reverse transcriptase inhibitors, were synthesized and resolved with different configurations. Biological results revealed that the trans-racemate 2b exhibited more potent activity than the cis-isomers. Noticeably, the trans-(S,S)-enantiomer 2e turned out to be significantly more potent than its counterpart enantiomer 2d against wild-type and double-mutant strains with high selectivity indexes.