143049-22-3

Usage

Uses

Used in Pharmaceutical Industry:
2,4-dioxo-1,2,3,4-tetrahydroquinoline-3-carboxylic acid is used as a key intermediate in the synthesis of new drugs for its structural features that can be modified to create bioactive compounds.
Used in Antimicrobial Applications:
In the medical field, 2,4-dioxo-1,2,3,4-tetrahydroquinoline-3-carboxylic acid is used as an antimicrobial agent due to its potential to inhibit the growth of various microorganisms, which can be beneficial in treating infections.
Used in Anti-inflammatory Applications:
2,4-dioxo-1,2,3,4-tetrahydroquinoline-3-carboxylic acid is also used as an anti-inflammatory agent, leveraging its potential to reduce inflammation and alleviate symptoms associated with inflammatory conditions.
Used in Materials Science:
2,4-dioxo-1,2,3,4-tetrahydroquinoline-3-carboxylic acid may be utilized in materials science for its unique structural properties that could contribute to the development of new materials with specific characteristics.
Further studies are essential to fully explore and validate the potential uses and properties of 2,4-dioxo-1,2,3,4-tetrahydroquinoline-3-carboxylic acid across different industries.

Upstream product

• 40059-53-8 ethyl 4-hydroxy-2-oxo-1,2-dihydroquinoline-3-carboxylate 
• 146828-48-0 2-carboethoxymalonanilic acid ethyl ester 
• 6315-94-2 ethyl 2,4-dichloroquinoline-3-carboxylate 
• 87-25-2 2-ethoxycarbonylaniline 
• 169216-63-1 2-ethoxy-4-hydroxyquinoline-3-carboxylic acid ethyl ester 
• 99429-64-8 ethyl ester of 4-chloro-2-oxo-1,2-dihydroquinoline-3-carboxylic acid 

Downstream Products

• 128366-03-0 1H-4-hydroxy-2-oxo-1,2-dihydroquinoline-3-carboxylic acid propylamide 
• 128366-05-2 4-hydroxyquinol-2-one-3-carboxylic acid n-butylamide 
• 128366-01-8 4-hydroxyquinol-2-one-3-carboxylic acid methylamide 

Relevant academic research and scientific papers

4-hydroxy-2-quinolones. 30. Alkylation of 1H-2-oxo-3-carbethoxy-4-hydroxyquinoline

A study has been made of the alkylation of 1H-2-oxo-3-carbethoxy-4-hydroxyquinoline by alkyl halides in the presence of inorganic bases. New methods for the synthesis of 1-substituted 2-oxo-3-carbethoxy-4-hydroxyquinolines are examined. 1997 Plenum Publishing Corporation.

4-HYDROXY-2-QUINOLONES. 20. SYNTHESIS AND CHEMICAL CONVERSIONS OF ETHYL ESTERS OF CHLORO-SUBSTITUTED QUINOLINE-3-CARBOXYLIC ACIDS

Preparative methods for the synthesis of ethyl esters of 2,4-dichloro- and 2-oxo-4-chloroquinoline-3-carboxylic acids were developed.The behavior of the compounds indicated was studied under conditions of alkaline and acidic hydrolysis, in reactions with some nucleophilic reagents, as well as in reductive dehalogenation.Results of the study of the antimicrobial and antiinflammatory activity of the synthesized compounds are presented.

4-Hydroxy-2-quinolones. 3. Synthesis and Physicochemical Properties of 1-R-3-Carbethoxy-4-hydroxy-2-quinolones

1-R-3-Carbethoxy-4-hydroxy-2-quinolones were synthesized by intramolecular cyclization of N-R-2-carbalkoxymalonanilic acids by the Dieckmann reaction.The possibility and advantages of conducting this reaction in aqueous medium were demonstrated.The mutual