143058-52-0Relevant articles and documents
Analogs of the δ opioid receptor selective cyclic peptide [2-D- penicillamine,5-D-penicillamine]-enkephalin: 2',6'-Dimethyltyrosine and Gly3-Phe4 amide bond isostere substitutions
Chandrakumar,Stapelfeld,Beardsley,Lopez,Drury,Anthony,Savage,Williamson,Reichman
, p. 2928 - 2938 (2007/10/02)
In order to develop systemically-active opioid peptides, the δ-selective, opioid pentapeptide [D-Pen2,D-Pen5]-enkephalin (DPDPE) was modified by esterification and by substitution of 2',6'-dimethyltyrosine for tyrosine to yield 4. Co