143059-77-2Relevant articles and documents
Asymmetric Alkylation of Chiral α,β-Unsaturated Lactones
Kato, Keisuke,Suemune, Hiroshi,Sakai, Kiyoshi
, p. 3481 - 3482 (1992)
Alkylation of 5, prepared from six-membered β-keto ester and (S,S)-cyclohexane-1,2-diol, proceeded in highly diastereoselective manner to afford quaternary carbon. - Key Words: (S,S)-cyclopentane-1,2-diol; (S,S)-cyclohexane-1,2-diol; asymmetric alkylation
PREPARATION OF OPTICALLY ACTIVE TRICYCLIC 1,4-DIOXEPIN-5-ONE DERIVATIVES AND ITS APPLICATION TO ASYMMETRIC ALKYLATION
Kato, Keisuke,Suemune, Hiroshi,Sakai, Kiyoshi
, p. 413 - 424 (2007/10/02)
Chiral bicyclic α,β-unsaturated lactones (6a,b and 8a,b) were easily synthesized from chiral cyclic diols (2-4) and cyclic β-keto esters (1a,b).Alkylation of 8b proceeded in a highly diastereoselective manner to afford a quaternary carbon.