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8-{4-[1-(2-tert-butoxy-2-oxoethyl)-1H-1,2,3-triazol-4-yl]phenyl}-4,4-di-fluoro-2,6-diiodo-1,3,5,7-tetramethyl-4-bora-3a,4a-diaza-s-indacene is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

1430657-59-2

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1430657-59-2 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 1430657-59-2 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,4,3,0,6,5 and 7 respectively; the second part has 2 digits, 5 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 1430657-59:
(9*1)+(8*4)+(7*3)+(6*0)+(5*6)+(4*5)+(3*7)+(2*5)+(1*9)=152
152 % 10 = 2
So 1430657-59-2 is a valid CAS Registry Number.

1430657-59-2Upstream product

1430657-59-2Downstream Products

1430657-59-2Relevant academic research and scientific papers

Synthesis and in vitro evaluation of a PDT active BODIPY-NLS conjugate

Verwilst, Peter,David, Charlotte C.,Leen, Volker,Hofkens, Johan,De Witte, Peter A.M.,De Borggraeve, Wim M.

, p. 3204 - 3207 (2013)

Two new photosensitizers based on the BODIPY scaffold have been synthesized, of which one bears an NLS peptide, which is linked to the BODIPY's core using the copper catalysed azide-alkyne click reaction. The phototoxicities of these BODIPY based photosensitizers have been determined, as well as their dark toxicities. Although the conjugation of a single NLS peptide to the BODIPY did not lead to any observable nuclear localization, the photosensitizer did exhibit a superior photoxicity. Cellular co-localization experiments revealed a localization of both dyes in the lysosomes, as well as a partial localization within the ER (for the peptide-bearing BODIPY).

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