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1430695-72-9

(E)-2-methoxy-5-(3-(5-methoxy-2,2-dimethyl-2H-chromen-8-yl)-3-oxoprop-1-en-1-yl)phenyl furan-2-carboxylate is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

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  • (E)-2-methoxy-5-(3-(5-methoxy-2,2-dimethyl-2H-chromen-8-yl)-3-oxoprop-1-en-1-yl)phenyl furan-2-carboxylate

    Cas No: 1430695-72-9

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  • 1430695-72-9 Structure

  • Basic information

    1. Product Name: (E)-2-methoxy-5-(3-(5-methoxy-2,2-dimethyl-2H-chromen-8-yl)-3-oxoprop-1-en-1-yl)phenyl furan-2-carboxylate
    2. Synonyms: (E)-2-methoxy-5-(3-(5-methoxy-2,2-dimethyl-2H-chromen-8-yl)-3-oxoprop-1-en-1-yl)phenyl furan-2-carboxylate
    3. CAS NO:1430695-72-9
    4. Molecular Formula:
    5. Molecular Weight: 460.483
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 1430695-72-9.mol

  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: N/A
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: (E)-2-methoxy-5-(3-(5-methoxy-2,2-dimethyl-2H-chromen-8-yl)-3-oxoprop-1-en-1-yl)phenyl furan-2-carboxylate(CAS DataBase Reference)
    10. NIST Chemistry Reference: (E)-2-methoxy-5-(3-(5-methoxy-2,2-dimethyl-2H-chromen-8-yl)-3-oxoprop-1-en-1-yl)phenyl furan-2-carboxylate(1430695-72-9)
    11. EPA Substance Registry System: (E)-2-methoxy-5-(3-(5-methoxy-2,2-dimethyl-2H-chromen-8-yl)-3-oxoprop-1-en-1-yl)phenyl furan-2-carboxylate(1430695-72-9)

  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 1430695-72-9(Hazardous Substances Data)

1430695-72-9 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 1430695-72-9 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,4,3,0,6,9 and 5 respectively; the second part has 2 digits, 7 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 1430695-72:
(9*1)+(8*4)+(7*3)+(6*0)+(5*6)+(4*9)+(3*5)+(2*7)+(1*2)=159
159 % 10 = 9
So 1430695-72-9 is a valid CAS Registry Number.

1430695-72-9Downstream Products

1430695-72-9Relevant articles and documents

(E)-1-(5-METHOXY-2,2-DIMETHYL-2H-CHROMEN-8-YL)-3-(4-METHOXYPHENYL)PROP-2-EN-1-ONE AND ANALOGS THEREOF, AS WELL AS PREPARATION METHOD AND USE THEREOF

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Paragraph 0276; 0277; 0288; 0289, (2015/05/26)

The present invention relates to millepachine ((E)-1-(5-methoxy-2,2-dimethyl-2H-chromen-8-yl)-3-(4-methoxyphenyl)prop-2-en-1-one) and its analogues. The present invention provides methods for preparing these compounds, pharmaceutical compositions includin

Synthesis and biological evaluation of novel pyranochalcone derivatives as a new class of microtubule stabilizing agents

Cao, Dong,Han, Xiaolei,Wang, Guangcheng,Yang, Zhuang,Peng, Fei,Ma, Liang,Zhang, Ronghong,Ye, Haoyu,Tang, Minghai,Wu, Wenshuang,Lei, Kai,Wen, Jiaolin,Chen, Jinying,Qiu, Jingxiang,Liang, Xiaolin,Ran, Yan,Sang, Yun,Xiang, Mingli,Peng, Aihua,Chen, Lijuan

, p. 579 - 589 (2013/05/09)

Twenty-five novel pyranochalcone derivatives were synthesized and evaluated for their in vitro and in vivo antiproliferative activities. Among them, compound 10i exhibited superior potent activity against 21 tumor cell lines including multidrug resistant phenotype with the IC50 values ranged from 0.09 to 1.30 μM. In addition, 10i significantly induced cell cycle arrest in G2/M phase, promoted tubulin polymerization into microtubules and caused microtubule stabilization. Further studies confirmed that 10i significantly suppressed the growth of tumor volume in HepG2 xenograft tumor model. Our study demonstrated that 10i could have beneficial antitumor activity as a novel microtubule stabilizing agent.

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