1430723-75-3

Upstream product

• 876732-44-4 4-azido-2-methylbutan-2-ol 
• 35979-69-2 4-bromo-2-methyl-2-butanol 
• 1430727-73-3 4-(4-(1-(5-amino-2',4'-difluorobiphenyl-3-yl)-1H-benzo[d]imidazol-5-yl)-1H-1,2,3-triazol-1-yl)-2-methylbutan-2-ol 
• 124-63-0 methanesulfonyl chloride 
• 1430723-74-2 N-(2',4'-difluoro-5-(5-(1-(3-hydroxy-3-methylbutyl)-1H-1,2,3-triazol-4-yl)-1H-benzo[d]imidazol-1-yl)biphenyl-3-yl)acetamide 
• 1430727-59-5 N-(5-(5-ethynyl-1H-benzo[d]imidazol-1-yl)-2',4'-difluorobiphenyl-3-yl)-acetamide 
• 1430727-57-3 N-(2',4'-difluoro-5-(5-((trimethylsilyl)ethynyl)-1H-benzo[d]imidazol-1-yl)-biphenyl-3-yl)acetamide 
• 1430727-56-2 N-(2',4'-difluoro-5-(5-iodo-1H-benzo[d]imidazol-1-yl)biphenyl-3-yl)acetamide 
• 1430727-54-0 N-(5-(2-amino-4-iodophenylamino)-2',4'-difluorobiphenyl-3-yl)acetamide 
• 1430727-53-9 N-(2',4'-difluoro-5-(4-iodo-2-nitrophenylamino)biphenyl-3-yl)acetamide 
• 1493-27-2 ortho-nitrofluorobenzene 
• 1430727-45-9 N-(5-amino-2',4'-difluorobiphenyl-3-yl)acetamide 
• 1430727-43-7 N-(2',4'-difluoro-5-nitrobiphenyl-3-yl)acetamide 
• 231287-74-4 N-(3-bromo-5-nitrophenyl)acetamide 

Relevant academic research and scientific papers

PROTEIN KINASE INHIBITORS

A compound of formula (I), wherein R3, R4, G, B, M, and Z are as defined in the claims, and pharmaceutically acceptable salts thereof are disclosed. The compounds of formula (I) possess utility as FGFR inhibitors and are useful in the treatment of a condition, where FGFR kinase inhibition is desired, such as cancer.

PROTEIN KINASE INHIBITORS

A compound of formula (I), wherein R3, R4, G, B, M, and Z are as defined in the claims, and pharmaceutically acceptable salts thereof are disclosed. The compounds of formula (I) possess utility as FGFR inhibitors and are useful in the treatment of a condition, where FGFR kinase inhibition is desired, such as cancer.