1430725-29-3

Upstream product

• 1430725-25-9 N-(5-(5-(1H-1,2,4-triazol-1-yl)-1H-benzo[d]imidazol-1-yl)-2',4'-difluoro-[1,1'-biphenyl]-3-yl)acetamide 
• 1430729-03-5 N-(5-((2-amino-4-(1H-1,2,4-triazol-1-yl)phenyl)amino)-2',4'-difluoro-[1,1'-biphenyl]-3-yl)acetamide 
• 1430729-02-4 N-(2',4'-difluoro-5-((2-nitro-4-(1H-1,2,4-triazol-1-yl)phenyl)amino)-[1,1'-biphenyl]-3-yl)acetamide 
• 1430729-04-6 5-(5-(1H-1,2,4-triazol-1-yl)-1H-benzo[d]imidazol-1-yl)-2',4'-difluoro-[1,1'-biphenyl]-3-amine 
• 802294-64-0 propionic acid 
• 1430727-56-2 N-(2',4'-difluoro-5-(5-iodo-1H-benzo[d]imidazol-1-yl)biphenyl-3-yl)acetamide 
• 1430727-54-0 N-(5-(2-amino-4-iodophenylamino)-2',4'-difluorobiphenyl-3-yl)acetamide 
• 1430727-53-9 N-(2',4'-difluoro-5-(4-iodo-2-nitrophenylamino)biphenyl-3-yl)acetamide 
• 1493-27-2 ortho-nitrofluorobenzene 
• 1430727-45-9 N-(5-amino-2',4'-difluorobiphenyl-3-yl)acetamide 
• 1430727-43-7 N-(2',4'-difluoro-5-nitrobiphenyl-3-yl)acetamide 
• 231287-74-4 N-(3-bromo-5-nitrophenyl)acetamide 
• 55215-57-1 1-amino-3-bromo-5-nitrobenzene 
• 99-65-0 meta-dinitrobenzene 

Relevant academic research and scientific papers

PROTEIN KINASE INHIBITORS

A compound of formula (I), wherein R3, R4, G, B, M, and Z are as defined in the claims, and pharmaceutically acceptable salts thereof are disclosed. The compounds of formula (I) possess utility as FGFR inhibitors and are useful in the treatment of a condition, where FGFR kinase inhibition is desired, such as cancer.

PROTEIN KINASE INHIBITORS

A compound of formula (I), wherein R3, R4, G, B, M, and Z are as defined in the claims, and pharmaceutically acceptable salts thereof are disclosed. The compounds of formula (I) possess utility as FGFR inhibitors and are useful in the treatment of a condition, where FGFR kinase inhibition is desired, such as cancer.