1430727-41-5Relevant academic research and scientific papers
Protected Chloroethyl and Chloropropyl Amines as Conformationally Unrestricted Annulating Reagents
Shi, Qing,Meehan, Mariah C.,Galella, Michael,Park, Hyunsoo,Khandelwal, Purnima,Hynes, John,Dhar, T. G. Murali,Marcoux, David
supporting information, p. 337 - 340 (2018/01/28)
The purpose of this letter is to document the use of protected chloroethyl and chloropropyl amines as conformationally unrestricted ambiphilic reagents that undergo annulation reactions with Michael acceptors. This reaction is wide in scope and utilizes r
PROTEIN KINASE INHIBITORS
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Page/Page column 31, (2014/10/18)
A compound of formula (I), wherein R1 to R5, A, B, Z, Z1 and Z2 are as defined in the claims, and pharmaceutically acceptable salts thereof are disclosed. The compounds of formula (I) possess utility as FGFR inhibitors and are useful in the treatment of a condition, where FGFR kinase inhibition is desired, such as cancer.
PROTEIN KINASE INHIBITORS
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Page/Page column 46; 47, (2013/04/25)
A compound of formula (I), wherein R3, R4, G, B, M, and Z are as defined in the claims, and pharmaceutically acceptable salts thereof are disclosed. The compounds of formula (I) possess utility as FGFR inhibitors and are useful in the treatment of a condition, where FGFR kinase inhibition is desired, such as cancer.
