1430812-53-5

Basic information

• Product Name: 4-({(E)-[4-(2,4-dichlorophenyl)-1H-pyrazol-3-yl]methylidene}amino)-5-[(naphthalen-1-yloxy)methyl]-4H-1,2,4-triazole-3-thiol
• Synonyms: 4-({(E)-[4-(2,4-dichlorophenyl)-1H-pyrazol-3-yl]methylidene}amino)-5-[(naphthalen-1-yloxy)methyl]-4H-1,2,4-triazole-3-thiol
• CAS NO: 1430812-53-5
• Molecular Weight: 495.392
• Mol File: 1430812-53-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 4-({(E)-[4-(2,4-dichlorophenyl)-1H-pyrazol-3-yl]methylidene}amino)-5-[(naphthalen-1-yloxy)methyl]-4H-1,2,4-triazole-3-thiol(CAS DataBase Reference)
• NIST Chemistry Reference: 4-({(E)-[4-(2,4-dichlorophenyl)-1H-pyrazol-3-yl]methylidene}amino)-5-[(naphthalen-1-yloxy)methyl]-4H-1,2,4-triazole-3-thiol(1430812-53-5)
• EPA Substance Registry System: 4-({(E)-[4-(2,4-dichlorophenyl)-1H-pyrazol-3-yl]methylidene}amino)-5-[(naphthalen-1-yloxy)methyl]-4H-1,2,4-triazole-3-thiol(1430812-53-5)

Safety Data

• Hazardous Substances Data: 1430812-53-5(Hazardous Substances Data)

Upstream product

• 24310-15-4 α-naphthoxyacetylhydrazine 
• 1031794-72-5 3-(2,4-dichlorophenyl)-1H-pyrazole-4-carbaldehyde 
• 137266-17-2 4-Amino-5-(naphthalen-1-yloxymethyl)-4H-[1,2,4]triazole-3-thiol 
• 163893-51-4 C₉H₉Cl₂N₃O 
• 2234-16-4 1-(2,4-dichlorophenyl)ethan-1-one 

Relevant articles and documents

New pyrazole derivatives containing 1,2,4-triazoles and benzoxazoles as potent antimicrobial and analgesic agents

Azole class of compounds are well known for their excellent therapeutic properties. Present paper describes about the synthesis of three series of new 1,2,4-triazole and benzoxazole derivatives containing substituted pyrazole moiety (11a-d, 12a-d and 13a-d). The newly synthesized compounds were characterized by spectral studies and also by C, H, N analyses. All the synthesized compounds were screened for their analgesic activity by the tail flick method. The antimicrobial activity of the new derivatives was also performed by Minimum Inhibitory Concentration (MIC) by the serial dilution method. The results revealed that the compound 11c having 2,5-dichlorothiophene substituent on pyrazole moiety and a triazole ring showed significant analgesic and antimicrobial activity.