143085-34-1Relevant articles and documents
Synthesis and properties of ring-deactivated deuterated (hydroxymethyl)pyrroles
Abell, Andrew D.,Nabbs, Brent K.,Battersby, Alan R.
, p. 1741 - 1746 (1998)
A sequence, based on a Mitsunobu displacement at the hydroxymethyl position of deuterium-labeled, N-substituted 2-(hydroxymethyl)pyrroles, is reported as a general procedure to determine the ability of the N-substituent to deactivate the heterocycle. An S
On the Mechanism of Porphobilinogen Deaminase. Design, Synthesis, and Enzymatic Reactions of Novel Porphobilinogen Analogs.
Pichon, Clotilde,Clemens, Karen R.,Jacobson, Alan R.,Scott, A. Ian
, p. 4687 - 4712 (2007/10/02)
Three new derivatives of porphobilinogen (PBG; 1) were designed and synthesized to study the mechanism of ammonia loss during the tetramerization of PBG, catalyzed by the PBG deaminase.Two of these compounds are substituted at the C-11 carbon with CH3 or
