143097-22-7

Upstream product

• 109-76-2 Trimethylenediamine 
• 6283-25-6 H₂NC₆H₃(Cl)NO₂ 
• 53666-48-1 N-(2-chloro-5-nitrophenyl)formamide 

Downstream Products

• 143097-21-6 2--1,2,3,4-tetrahydropyrimidine 
• 1173978-57-8 9-chloro-1-(2,4-dichlorophenyl)-1,2,3,4-tetrahydropyrimido[1,2-a]benzimidazol-6-amine 
• 1173978-58-9 9-chloro-1-(2,4-dichlorophenyl)-N,N-diethyl-1,2,3,4-tetrahydropyrimido[1,2-a]benzimidazol-6-amine 
• 1173978-56-7 9-chloro-1-(2,4-dichlorophenyl)-6-nitro-1,2,3,4-tetrahydropyrimido[1,2-a]benzimidazole 

Relevant academic research and scientific papers

Discovery of 1,2,3,4-tetrahydropyrimido[1,2-a]benzimidazoles as novel class of corticotropin releasing factor 1 receptor antagonists

A new class of corticotropin releasing factor 1 (CRF1) receptor antagonists characterized by a tricyclic core ring was designed and synthesized. Novel tricyclic derivatives 2a–e were designed as CRF1 receptor antagonists based on con

Cyclic guanidines; IV. Intramolecular nucleophilic aromatic substitution of hydrogen in (3-nitrophenyl)guanidines

Cyclization of substituted (3-nitrophenyl)guanidines is achieved in basic medium by nucleophilic displacement of hydrogen. The reaction offers a new route to benzimidazoles as well as to tricyclic imidazo-, pyrimido- and diazepino-benzimidazoles with unco