1431137-91-5Relevant articles and documents
Synthesis and biological activity of 25-hydroxy-2-methylene-vitamin D3 analogues monohydroxylated in the A-ring
Sibilska, Izabela K.,Sicinski, Rafal R.,Ochalek, Justin T.,Plum, Lori A.,Deluca, Hector F.
, p. 8319 - 8331 (2014/12/11)
The 20R- and 20S-isomers of 25-hydroxy-2-methylene-vitamin D3 and 3-desoxy-1α,25-dihydroxy-2-methylene-vitamin D3 have been synthesized. Two alternative synthetic routes were devised for preparation of the required A-ring synthons, s
2-METHYLENE-VITAMIN D ANALOGS AND THEIR USES
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Paragraph 0050; 0051; 0052; 0053, (2013/05/08)
This invention discloses 2-methylene-vitamin D analogs, and specifically (20S)-25-hydroxy-2-methylene-vitamin D3 and (20R)-25-hydroxy-2-methylene-vitamin D3, as well as pharmaceutical uses therefor. These compounds exhibit relatively