143128-42-1

Basic information

• Product Name: Methanone, [4-[[3-fluoro-5-(tetrahydro-4-methoxy-2H-pyran-4-yl)phenyl]thio]phenyl](4 -hydroxyphenyl)-
• CAS NO: 143128-42-1
• Molecular Formula: C25H23FO4S
• Molecular Weight: 438.52
• Mol File: 143128-42-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: Methanone, [4-[[3-fluoro-5-(tetrahydro-4-methoxy-2H-pyran-4-yl)phenyl]thio]phenyl](4 -hydroxyphenyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Methanone, [4-[[3-fluoro-5-(tetrahydro-4-methoxy-2H-pyran-4-yl)phenyl]thio]phenyl](4 -hydroxyphenyl)-(143128-42-1)
• EPA Substance Registry System: Methanone, [4-[[3-fluoro-5-(tetrahydro-4-methoxy-2H-pyran-4-yl)phenyl]thio]phenyl](4 -hydroxyphenyl)-(143128-42-1)

Safety Data

• Hazardous Substances Data: 143128-42-1(Hazardous Substances Data)

Upstream product

• 135715-84-3 4-(5-fluoro-3-mercaptophenyl)-4-methoxytetrahydropyran 
• 143148-08-7 4-[3-(4-(4-(3-dimethylaminopropoxy)benzoyl)-phenylthio)-5-fluorophenyl]-4-methoxytetrahydropyran 
• 25913-05-7 4-fluoro-4'-hydroxybenzophenone 

Relevant articles and documents

ARYL DERIVATIVES

The invention concerns an aryl derivative of the formula I, wherein Ar1 is optionally substituted phenyl, naphthyl or a heterocyclic moiety, and X1 is oxy, thio, sulphinyl, sulphonyl, difluoromethylene, imino, (1-4C)alkylimino or optionally substituted (1-4C) alkylene, or X1 is a group of the formula wherein X4 is oxy, thio, sulphinyl, sulphonyl or carbonyl and each R is hydrogen, methyl or ethyl each of Ar2 and Ar3 is optionally substituted phenylene X2 is oxy, thio, sulphinyl or sulphonyl R1 is (1-4C)alkyl and R2 and R3 together form a group of the formula A1 X3 A2 which together with the carbon atom to which A1 and A2 are attached define a ring having 5 to 7 ring atoms, wherein each of A1 and A2 is (1-3C) alkylene and X3 is oxy, thio, sulphinyl or sulphonyl which compounds are inhibitors of 5-lipoxygenase and are useful in the treatment of inflammatory or allergic disease