1431319-98-0

Basic information

• Product Name: 6-chloro-N'-(2-chlorophenylsulfonyl)pyrazine-2-carboximidamide
• CAS NO: 1431319-98-0
• Molecular Weight: 331.182
• Mol File: 1431319-98-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 6-chloro-N'-(2-chlorophenylsulfonyl)pyrazine-2-carboximidamide(CAS DataBase Reference)
• NIST Chemistry Reference: 6-chloro-N'-(2-chlorophenylsulfonyl)pyrazine-2-carboximidamide(1431319-98-0)
• EPA Substance Registry System: 6-chloro-N'-(2-chlorophenylsulfonyl)pyrazine-2-carboximidamide(1431319-98-0)

Safety Data

• Hazardous Substances Data: 1431319-98-0(Hazardous Substances Data)

Upstream product

• 1246466-46-5 C₆H₆ClN₃O 
• 6961-82-6 2-chlorobenzenesulfonamide 
• 6863-74-7 6-chloropyrazine-2-carbonitrile 

Relevant articles and documents

Synthesis, structure, and biological activity of novel heterocyclic sulfonyl-carboximidamides

A series of novel heterocyclic sulfonyl-carboximidamides were synthesized in satisfactory yields via condensation of heterocyclic methyl carbimidates with 2-chlorobenzenesulfonamide and 4-chloropyridine-3-sulfonamide. New structures were confirmed by IR and NMR spectra as well as elemental analyses. X-ray crystallography of two derivatives was performed. The single-crystal structures confirmed the presence of a primary amine group in the amidine moiety. All the compounds were screened for their tuberculostatic, antibacterial, and anticancer activities. Preliminary results indicated that target compounds exhibited weak tuberculostatic and antibacterial activities. Seven compounds inhibited the growth of some cancer cell lines, whereas one of the 2-quinoline derivatives displayed favorable activity against all tested cancer cells with GI 50 values of 0.92-13 μM.