1431328-95-8

Basic information

• Product Name: (E)-methyl 1-(3-(2-bromo-5-fluorophenyl)-2-(tert-butoxycarbonyl)allyl)-3-cyclohexyl-1H-indole-6-carboxylate
• Synonyms: (E)-methyl 1-(3-(2-bromo-5-fluorophenyl)-2-(tert-butoxycarbonyl)allyl)-3-cyclohexyl-1H-indole-6-carboxylate
• CAS NO: 1431328-95-8
• Molecular Weight: 570.499
• Mol File: 1431328-95-8.mol

Chemical Properties

• CAS DataBase Reference: (E)-methyl 1-(3-(2-bromo-5-fluorophenyl)-2-(tert-butoxycarbonyl)allyl)-3-cyclohexyl-1H-indole-6-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: (E)-methyl 1-(3-(2-bromo-5-fluorophenyl)-2-(tert-butoxycarbonyl)allyl)-3-cyclohexyl-1H-indole-6-carboxylate(1431328-95-8)
• EPA Substance Registry System: (E)-methyl 1-(3-(2-bromo-5-fluorophenyl)-2-(tert-butoxycarbonyl)allyl)-3-cyclohexyl-1H-indole-6-carboxylate(1431328-95-8)

Safety Data

• Hazardous Substances Data: 1431328-95-8(Hazardous Substances Data)

Upstream product

• 1431328-93-6 tert-butyl 2-((2-bromo-5-fluorophenyl)(hydroxy)methyl)acrylate 
• 1663-39-4 tert-Butyl acrylate 
• 94569-84-3 2-bromo-5-fluorobenzaldehyde 
• 494799-18-7 methyl 3-cyclohexyl-1H-indole-6-carboxylate 
• 1431328-94-7 tert-butyl 2-(acetoxy(2-bromo-5-fluorophenyl)methyl)acrylate 

Downstream Products

• 1431328-98-1 5-methyl 1a-(2-methyl-2-propanyl)(1aR,12bS)-8-cyclohexyl-11-fluoro-1,12b-dihydrocyclopropa[d]indolo[2,1-a][2]benzazepine-1a,5(2H)-dicarboxylate 
• 1431328-99-2 (1aS,12bR)-8-cyclohexyl-11-fluoro-5-(methoxycarbonyl)-1,12b-dihydrocyclopropa[d]indolo[2,1-a][2]benzazepine-1a(2H)-carboxylic acid 

Relevant articles and documents

(1aR,12bS)-8-cyclohexyl-11-fluoro-N-((1-methylcyclopropyl)sulfonyl)-1a-((3-methyl-3,8-diazabicyclo[3.2.1]oct-8-yl)carbonyl)-1,1a,2,2b-tetrahydrocyclopropa[d]indolo[2,1-a][2]benzazepine-5-carboxamide for use in treating HCV

The invention relates to an administration unit comprising a compound of formula and/or pharmaceutically acceptable salts thereof, and to a packaging comprising the administration unit according to the invention.

Novel Compound for the Treatment of Hepatitis C

The present invention provides (1aR,12bS)-8-cyclohexyl-11-fluoro-N-((1-methylcyclopropyl)sulfonyl)-1a-((3-methyl-3,8-diazabicyclo[3.2.1]oct-8-yl)carbonyl)-1,1a,2,12b-tetrahydrocyclopropa[d]indolo[2,1-a][2]benzazepine-5-carboxamide (formula I), including pharmaceutically acceptable salts, as well as compositions and methods of using the compound. The compound has activity against hepatitis C virus (HCV) and may be useful in treating those infected with HCV.