143142-34-1

Basic information

• Product Name: 3-Pyridinecarboxaldehyde, 6-propyl- (9CI)
• Synonyms: 3-Pyridinecarboxaldehyde, 6-propyl- (9CI);6-propylnicotinaldehyde;6-Propylpyridin-3-carbaldehyde
• CAS NO: 143142-34-1
• Molecular Formula: C₉H₁₁NO
• Molecular Weight: 149.18974
• Product Categories: PYRIDINE;ALDEHYDE
• Mol File: 143142-34-1.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 3-Pyridinecarboxaldehyde, 6-propyl- (9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Pyridinecarboxaldehyde, 6-propyl- (9CI)(143142-34-1)
• EPA Substance Registry System: 3-Pyridinecarboxaldehyde, 6-propyl- (9CI)(143142-34-1)

Safety Data

• Hazardous Substances Data: 143142-34-1(Hazardous Substances Data)

Upstream product

• 847046-96-2 6-propylnicotinic acid 
• 149281-42-5 6-chloro-N-methoxy-N-methylpyridine-3-carboxamide 
• 73781-91-6 6-Chloronicotinic acid methyl ester 
• 118419-90-2 Ethyl 6-propylnicotinate 
• 17745-45-8 propylboronic acid 
• 149806-06-4 6-bromonicotinaldehyde 

Downstream Products

• 1318897-70-9 C₂₆H₃₉N₃O 
• 118420-48-7 N-{4-[4-(Diphenylmethyl)-1-piperazinyl]butyl}-3-(6-propyl-3-pyridyl)acrylamide 

Relevant articles and documents

ISOQUINOLINE DERIVATIVES AS MGAT2 INHIBITORS

The compounds of Formula I act as MGAT2 inhibitors and can be useful in preventing, treating or acting as a remedial agent for hyperlipidemia, diabetes mellitus and obesity.

Acrylamide derivatives as antiallergic agents. 2. Synthesis and structure-activity relationships of N-[4-[4-(diphenylmethyl)-1-piperazinyl]butyl]-3-(3-pyridyl)acrylamides

A new series of 3-(3-pyridyl)acrylamides 16, 17, 19, and 26, and 5-(3-pyridyl)-2,4-pentadienamides 20-25 were prepared and evaluated for their antiallergic activity. Several of these compounds exhibited more potent inhibitory activities than the parent compounds 1a [(E)-N-[4 [4-(diphenylmethyl)-1-piperazinyl]butyl]-3-(3-pyridyl)acrylamide] against the rat passive cutaneous anaphylaxis (PCA) reaction and the enzyme 5-lipoxygenase. Particularly, 4-[4-(diphenylmethyl)-1-piperazinyl]butyl]-3-(6-methyl-3-pyridyl)acrylamide (17p) showed an ED50 value of 3.3 mg/kg po in the rat PCA test, which was one-fifth of ketotifen and oxatomide. As compared with ketotifen and oxatomide, compound 17p (AL-3264) possessed a better balance of antiallergic properties due to inhibition of chemical mediator release, inhibition of 5-lipoxygenase, and antagonism of histamine.