1431563-80-2Relevant academic research and scientific papers
Sequential C-H functionalization reactions for the enantioselective synthesis of highly functionalized 2,3-dihydrobenzofurans
Wang, Hengbin,Li, Gang,Engle, Keary M.,Yu, Jin-Quan,Davies, Huw M. L.
supporting information, p. 6774 - 6777 (2013/06/05)
The enantioselective synthesis of 2,3-dihydrobenzofurans was achieved by using two sequential C-H functionalization reactions, a rhodium-catalyzed enantioselective intermolecular C-H insertion followed by a palladium-catalyzed C-H activation/C-O cyclization. Further diversification of the 2,3-dihydrobenzofuran structures was possible by a subsequent palladium-catalyzed intermolecular Heck-type sp2 C-H functionalization.
