143159-84-6

Upstream product

• 90821-68-4 (E)-2-[(2R,3R)-2-(Benzothiazol-2-yldisulfanyl)-4-oxo-3-(2-phenoxy-acetylamino)-azetidin-1-yl]-3-hydroxy-but-2-enoic acid 4-nitro-benzyl ester 
• 57561-85-0 (R)-2-[(2R)-2r-benzothiazol-2-yldisulfanyl-4-oxo-3c-(2-phenoxy-acetylamino)-azetidin-1-yl]-3-methyl-but-3-enoic acid 4-nitro-benzyl ester 
• 149-30-4 2-Mercaptobenzothiazole 
• 41625-65-4 4-nitrobenzyl(2S,4S,5R,6R)-3,3-dimethyl-7-oxo-6-phenoxyacetamido-1-aza-4-thiabicyclo<3.2.0>heptane-2-carboxylate 4-oxide 
• 143159-83-5 (E)-2-[(2R,3R)-2-(Benzothiazol-2-yldisulfanyl)-4-oxo-3-(2-phenoxy-acetylamino)-azetidin-1-yl]-3-trifluoromethanesulfonyloxy-but-2-enoic acid 4-nitro-benzyl ester 

Relevant academic research and scientific papers

A new strategy for the conversion of penams into cephems via allene chemistry

We describe an extension of the Morin rearrangement in which 3-norcephalosporins bearing sulfur substituents at C(3) are obtained directly from an allenic intermediate, which is efficiently prepared from penicillin V sulfoxide.

Processes for making cephems from allenylazetidinone derivatives

This invention relates to a novel process for making a cephem of formula II from 2-(3-amino-2-oxo-azetidin-1-yl)-2,3-butadienoate of formula I. In another aspect, this invention is concerned with a process of further converting a compound of formula II in