1431660-32-0Relevant articles and documents
Dearomative radical spirocyclization from N-ce: Raghubenzyltrichloroacetamides revisited using a copper(I)-mediated atom transfer reaction leading to 2-azaspiro[4.5]decanes
Diaba, Fa?za,Montiel, Juan A.,Martínez-Laporta, Agustín,Bonjoch, Josep
, p. 2619 - 2622 (2013/06/05)
An atom transfer radical dearomatizing spirocyclization from N-benzyltrichloroacetamides using CuCl regioselectively leads to 2-azaspiro[4.5]decadienes, in which the labile allylic chlorine atom is easily replaced by a hydroxyl group in aqueous medium or by quenching with methanol or allylamine. After oxidation of the target compound, the N-tert-butyl group can be removed from the resulting spirocyclohexanedienone.