1431664-75-3

Basic information

• Product Name: 8-methyl-4-oxo-2-phenyl-4H-chromen-7-yl benzoate
• Synonyms: 8-methyl-4-oxo-2-phenyl-4H-chromen-7-yl benzoate
• CAS NO: 1431664-75-3
• Molecular Weight: 356.378
• Mol File: 1431664-75-3.mol

Chemical Properties

• CAS DataBase Reference: 8-methyl-4-oxo-2-phenyl-4H-chromen-7-yl benzoate(CAS DataBase Reference)
• NIST Chemistry Reference: 8-methyl-4-oxo-2-phenyl-4H-chromen-7-yl benzoate(1431664-75-3)
• EPA Substance Registry System: 8-methyl-4-oxo-2-phenyl-4H-chromen-7-yl benzoate(1431664-75-3)

Safety Data

• Hazardous Substances Data: 1431664-75-3(Hazardous Substances Data)

Upstream product

• 608-25-3 2-methylbenzene-1,3-diol 
• 10139-84-1 1-(2,4-dihydroxy-3-methylphenyl)ethanone 
• 100410-78-4 3-hydroxy-2-methyl-4-(3-oxo-3-phenylpropanoyl)phenyl benzoate 
• 98-88-4 benzoyl chloride 

Downstream Products

• 36747-88-3 7-hydroxy-8-methyl-2-phenyl-4H-benzofuro<3,2-g><1>benzopyran-4-one 
• 1431664-76-4 7-(2-bromoethoxy)-8-methyl-2-phenyl-4H-chromen-4-one 
• 1431664-86-6 7-(3-bromopropoxy)-8-methyl-2-phenyl-4H-chromen-4-one 
• 1431664-87-7 7-(4-bromobutoxy)-8-methyl-2-phenyl-4H-chromen-4-one 
• 1431664-88-8 7-((5-bromopentyl)oxy)-8-methyl-2-phenyl-4H-chromen-4-one 
• 1431664-89-9 7-((6-bromohexyl)oxy)-8-methyl-2-phenyl-4H-chromen-4-one 
• 1431664-77-5 C₂₂H₂₃NO₃ 
• 1431664-90-2 C₂₃H₂₅NO₃ 
• 1431664-91-3 C₂₄H₂₇NO₃ 
• 1431664-92-4 C₂₅H₂₉NO₃ 
• 1431664-78-6 C₂₄H₂₇NO₃ 
• 1431664-95-7 C₂₆H₃₁NO₃ 
• 1431664-94-6 C₂₅H₂₉NO₃ 
• 1431664-96-8 C₂₇H₃₃NO₃ 

Relevant articles and documents

Design and development of some thiazole-based flavanoids as novel antibacterial against pathogens causing surgical site infection for possible benefit in bone trauma via inhibition of DNA gyrase

In this study, a novel class of hybrid thiazole-based flavanoid derivatives were synthesized and characterized by FT-IR, 1H-NMR, 13C-NMR, mass and elemental analysis. These derivatives were evaluated for antibacterial activity for possible benefit in bone trauma via inhibition of DNA gyrase enzyme. Results suggested that compounds 9n, 9o, and 9p showed considerable inhibition of DNA gyrase with considerable activity against tested forty strains of Staphylococcus aureus clinical isolates. Moreover, compound 9n showed hydrogen bonding with LYS460 along with low binding free energy of ?4.36?kcal/mol against DNA gyrase enzyme. The hemolytic activity of the potent compounds showed mild to no activity together with excellent pharmacokinetics, suggesting to have a potential for the development of designed compounds as novel antibacterial agents.

Design, synthesis and evaluation of flavonoid derivatives as potential multifunctional acetylcholinesterase inhibitors against Alzheimer's disease

A new series of flavonoid derivatives were designed, synthesized and evaluated as potential multifunctional AChE inhibitors against Alzheimer's disease. Most of them exhibited potent AChE inhibitory activity, high selectivity for AChE over BuChE, and mode