1431767-74-6

Basic information

• Product Name: (S)-tert-butyl 3-(2-(2-bromo-N-(1-phenylethyl)acetamido)ethyl)-1H-indole-1-carboxylate
• Synonyms: (S)-tert-butyl 3-(2-(2-bromo-N-(1-phenylethyl)acetamido)ethyl)-1H-indole-1-carboxylate
• CAS NO: 1431767-74-6
• Molecular Weight: 485.421
• Mol File: 1431767-74-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (S)-tert-butyl 3-(2-(2-bromo-N-(1-phenylethyl)acetamido)ethyl)-1H-indole-1-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-tert-butyl 3-(2-(2-bromo-N-(1-phenylethyl)acetamido)ethyl)-1H-indole-1-carboxylate(1431767-74-6)
• EPA Substance Registry System: (S)-tert-butyl 3-(2-(2-bromo-N-(1-phenylethyl)acetamido)ethyl)-1H-indole-1-carboxylate(1431767-74-6)

Safety Data

• Hazardous Substances Data: 1431767-74-6(Hazardous Substances Data)

Upstream product

• 1431767-73-5 (S)-(tert-butyl) 3-(2-(1-phenylethylamino)ethyl)-1H-indole-1-carboxylate 
• 598-21-0 2-Bromoacetyl bromide 
• 3389-21-7 3-(2-bromoethyl)-1H-indole 
• 24424-99-5 di-tert-butyl dicarbonate 
• 131829-28-2 3-(2-bromoethyl)indole-1-carboxylic acid tert-butyl ester 

Downstream Products

• 1431767-75-7 (S)-(2-((2-(1-(tert-butoxycarbonyl)-1H-indol-3-yl)ethyl)(1-phenylethyl)amino)-2-oxoethyl)dimethylsulfonium bromide 
• 1431767-78-0 (5S,6R)-(tert-butyl) 5-hydroxy-4-oxo-6-phenyl-3-[(S)-1-phenylethyl]-3,4,5,6-tetrahydro-1H-azocino[5,4-b]indole-7(2H)-carboxylate 
• 1431767-79-1 (5R,6S)-(tert-butyl) 5-hydroxy-4-oxo-6-phenyl-3-[(S)-1-phenylethyl]-3,4,5,6-tetrahydro-1H-azocino[5,4-b]indole-7(2H)-carboxylate 
• 1431767-80-4 (5S,6R)-tert-butyl 5-hydroxy-6-(2-nitrophenyl)-4-oxo-3-((S)-1-phenylethyl)-3,4,5,6-tetrahydro-1H-azocino[5,4-b]indole-7(2H)-carboxylate 
• 1431767-81-5 (5S,6R)-tert-butyl 5-hydroxy-6-(3-nitrophenyl)-4-oxo-3-((S)-1-phenylethyl)-3,4,5,6-tetrahydro-1H-azocino[5,4-b]indole-7(2H)-carboxylate 
• 1431767-82-6 (5R,6S)-tert-butyl 5-hydroxy-6-(3-nitrophenyl)-4-oxo-3-((S)-1-phenylethyl)-3,4,5,6-tetrahydro-1H-azocino[5,4-b]indole-7(2H)-carboxylate 
• 1431767-83-7 (5S,6R)-tert-butyl 5-hydroxy-6-(4-nitrophenyl)-4-oxo-3-((S)-1-phenylethyl)-3,4,5,6-tetrahydro-1H-azocino[5,4-b]indole-7(2H)-carboxylate 
• 1431767-84-8 (5R,6S)-tert-butyl 5-hydroxy-6-(4-nitrophenyl)-4-oxo-3-((S)-1-phenylethyl)-3,4,5,6-tetrahydro-1H-azocino[5,4-b]indole-7(2H)-carboxylate 
• 1431767-86-0 (5S,6R)-tert-butyl 6-ethyl-5-hydroxy-4-oxo-3-((S)-1-phenylethyl)-3,4,5,6-tetrahydro-1H-azocino[5,4-b]indole-7(2H)-carboxylate 
• 1431767-87-1 (5S,6R)-tert-butyl 5-hydroxy-4-oxo-3-((S)-1-phenylethyl)-6-propyl-3,4,5,6-tetrahydro-1H-azocino[5,4-b]indole-7(2H)-carboxylate 
• 1431767-76-8 C₃₂H₃₂N₂O₃ 
• 1431767-77-9 C₃₂H₃₁N₃O₅ 
• 1431767-88-2 (5S,6R)-5-hydroxy-6-phenyl-1,2,3,5,6,7-hexahydro-4H-azocino[5,4-b]indol-4-one 
• 1431767-89-3 (5S,6R)-5-hydroxy-6-phenyl-3-[(S)-1-phenylethyl]-2,3,5,6-tetrahydro-1H-azocino[5,4-b]indol-4(7H)-one 

Relevant articles and documents

Synthesis of the indoloazocine derivatives from a chiral indol amide-stabilized sulfur ylide

We present here a synthetic route for the access to a series of diverse indoloazocine derivatives through selective epoxidation of chiral sulfonium salt 4, which reacts with diverse aromatic and aliphatic aldehydes to give trans-glycidic amides, followed by an intramolecular electrophilic aromatic substitution promoted by Cu(OTf)2 giving the desired heterocyclic compound in a high chemical yield. Using this strategy, the total synthesis of (S,R)-(+)-norbalasubramide was achieved.