1431767-88-2

Basic information

• Product Name: (5S,6R)-5-hydroxy-6-phenyl-1,2,3,5,6,7-hexahydro-4H-azocino[5,4-b]indol-4-one
• Synonyms: (5S,6R)-5-hydroxy-6-phenyl-1,2,3,5,6,7-hexahydro-4H-azocino[5,4-b]indol-4-one
• CAS NO: 1431767-88-2
• Molecular Weight: 306.364
• Mol File: 1431767-88-2.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: (5S,6R)-5-hydroxy-6-phenyl-1,2,3,5,6,7-hexahydro-4H-azocino[5,4-b]indol-4-one(CAS DataBase Reference)
• NIST Chemistry Reference: (5S,6R)-5-hydroxy-6-phenyl-1,2,3,5,6,7-hexahydro-4H-azocino[5,4-b]indol-4-one(1431767-88-2)
• EPA Substance Registry System: (5S,6R)-5-hydroxy-6-phenyl-1,2,3,5,6,7-hexahydro-4H-azocino[5,4-b]indol-4-one(1431767-88-2)

Safety Data

• Hazardous Substances Data: 1431767-88-2(Hazardous Substances Data)

Upstream product

• 3389-21-7 3-(2-bromoethyl)-1H-indole 
• 131829-28-2 3-(2-bromoethyl)indole-1-carboxylic acid tert-butyl ester 
• 1431767-73-5 (S)-(tert-butyl) 3-(2-(1-phenylethylamino)ethyl)-1H-indole-1-carboxylate 
• 1446317-27-6 (S,E)-(tert-butyl) 3-((cinnamyl(1-phenylethyl)amino)ethyl)-1H-indole-1-carboxylate 
• 1431767-78-0 (5S,6R)-(tert-butyl) 5-hydroxy-4-oxo-6-phenyl-3-[(S)-1-phenylethyl]-3,4,5,6-tetrahydro-1H-azocino[5,4-b]indole-7(2H)-carboxylate 
• 1431767-89-3 (5S,6R)-5-hydroxy-6-phenyl-3-[(S)-1-phenylethyl]-2,3,5,6-tetrahydro-1H-azocino[5,4-b]indol-4(7H)-one 
• 1431767-75-7 (S)-(2-((2-(1-(tert-butoxycarbonyl)-1H-indol-3-yl)ethyl)(1-phenylethyl)amino)-2-oxoethyl)dimethylsulfonium bromide 
• 1431767-74-6 (S)-tert-butyl 3-(2-(2-bromo-N-(1-phenylethyl)acetamido)ethyl)-1H-indole-1-carboxylate 
• 14371-10-9 (E)-3-phenylpropenal 
• 115794-66-6 trans-methyl 3-phenylglycidate 

Relevant articles and documents

Application and preparation method of Balasubramide derivatives

The invention discloses application and preparation method of Balasubramide derivatives. The structural formulas of the Balasubramide derivatives are as shown in a formula (I); and the Balasubramide derivatives are excellent in nerve cell inflammation res

The use of sodium chlorite in the direct synthesis of glycidic amides: Enantiopure synthesis of both enantiomers of norbalasubramide

Recently, the first direct method for preparing 2,3-epoxyamides (glycidic amides) was disclosed. Now in this letter, the enantiopure synthesis of both enantiomers of norbalasubramide featuring this synthetic method is reported. To this end, chiral N-allyltryptamine 12 was prepared and transformed into an inseparable mixture of diastereomeric epoxyamides 13a/13b, which were submitted to intramolecular cyclization with Cu(OTf)2 to afford a separable mixture of eight-membered ring lactams 14a and 14b. Finally, after removal of the protective group and the chiral auxiliary an enantiopure synthesis of the title compounds was completed. Georg Thieme Verlag Stuttgart · New York.