1432044-38-6

Basic information

• Product Name: 2'-(1-benzyl-1H-tetrazol-5-yl)-[1,1'-biphenyl]-4-yl(phenyl)methanone
• Synonyms: 2'-(1-benzyl-1H-tetrazol-5-yl)-[1,1'-biphenyl]-4-yl(phenyl)methanone
• CAS NO: 1432044-38-6
• Molecular Weight: 416.482
• Mol File: 1432044-38-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2'-(1-benzyl-1H-tetrazol-5-yl)-[1,1'-biphenyl]-4-yl(phenyl)methanone(CAS DataBase Reference)
• NIST Chemistry Reference: 2'-(1-benzyl-1H-tetrazol-5-yl)-[1,1'-biphenyl]-4-yl(phenyl)methanone(1432044-38-6)
• EPA Substance Registry System: 2'-(1-benzyl-1H-tetrazol-5-yl)-[1,1'-biphenyl]-4-yl(phenyl)methanone(1432044-38-6)

Safety Data

• Hazardous Substances Data: 1432044-38-6(Hazardous Substances Data)

Upstream product

• 90-90-4 (4-bromophenyl)(phenyl)methanone 
• 28386-90-5 5-benzyl-1-phenyl-1H-tetrazole 

Relevant articles and documents

Carboxylate-assisted ruthenium(II)-catalyzed C-H arylations of 5-aryl tetrazoles: Step-economical access to Valsartan

Carboxylate assistance was key to success for highly efficient ruthenium-catalyzed direct ortho-arylations of tetrazolyl-substituted arenes with aryl halides and triflates in the absence of phosphine ligands. Thus, ruthenium(II) biscarboxylates allowed for C-H bond functionalizations with excellent chemo- and site-selectivities, which set the stage for an atom- and step-economical access to key angiotensin-II-receptor blockers. Mechanistic studies revealed the C-H bond metalation to be reversible, and were suggestive of a rate-determining reductive elimination.