1432097-27-2

Upstream product

• 1432048-81-1 {3,3-dimethoxy-1-[4-(trifluoromethoxy)phenyl]cyclobutyl}(pyridin-2-yl)-methanone 
• 1432048-78-6 methyl 3,3-dimethoxy-1-[4-(trifluoromethoxy)phenyl]cyclobutane-carboxylate 
• 1432048-77-5 3,3-dimethoxy-1-[4-(trifluoromethoxy)phenyl]cyclobutanecarboxamide 
• 49561-96-8 (4-trifluoromethoxy-phenyl)-acetonitrile 

Downstream Products

• 1432048-80-0 cis-3-[(S)-hydroxy(pyridin-2-yl)methyl]-3-[4-(trifluoromethoxy)phenyl]-cyclobutanol hydrochloride 
• 1432048-82-2 (trans)-3-[(S)-hydroxy(pyridin-2-yl)methyl]-3-[4-(trifluoromethoxy)-phenyl]cyclobutanol hydrochloride 

Relevant academic research and scientific papers

NOVEL TRPV3 MODULATORS

Disclosed herein are modulators of TRPV3 of Formula (I) wherein p is 1, 2, 3, or 4, and G1, X1, X2, X3, X4, X5, G2, Z1, Ra, Rb, and u are as defined in the specification. Compositions comprising such compounds and methods for treating conditions and disorders using such compounds and compositions are also presented.

NOVEL TRPV3 MODULATORS

Disclosed herein are modulators of TRPV3 of Formula (I) (I) wherein p is 1, 2, 3, or 4, and G1, X1, X2, X3, X 4, X5, G2, Z1, Ra, Rb, and u are as defined in the specification. Compositions comprising such compounds and methods for treating conditions and disorders using such compounds and compositions are also presented.