143237-34-7Relevant academic research and scientific papers
Intermolecular Benzyne Cycloaddition (IBC), a Versatile Approach to Benzophenanthridine Antitumor Alkaloids. Formal Synthesis of Nitidine and Chelerythrine
Martin, Gloria,Guitian, Enrique,Castedo, Luis,Saa, Jose M.
, p. 5907 - 5911 (1992)
A new approach to the synthesis of benzophenanthridine alkaloids is described which is based on cycloaddition of arynes to pyrrolinediones, the pyrrolinediones behaving as aza diene equivalents.The synthesis of 2,3,8,9-substituted benzophenanthridines and the regioselective synthesis of a 2,3,7,8-substituted benzophenanthridine were performed.The formal synthesis of chelerythrine and the antitumor alkaloid nitidine is described.
