143262-22-0Relevant academic research and scientific papers
DIRECTED LITHIATION OF 1-(tert-BUTOXYCARBONYL)INDOLINES. A CONVENIENT ROUTE TO 7-SUBSTITUTED INDOLINES
Iwao, Masatomo,Kuraishi, Tsukasa
, p. 1031 - 1038 (1992)
1-(tert-Butoxycarbonyl)indolines were regioselectively lithiated at 7-position with s-BuLi-TMEDA in ether or THF at -78 deg C.The lithiated species were reacted with a range of electrophiles to give 7-substituted indoline derivatives.
