143264-41-9

Upstream product

• 18107-18-1 diazomethyl-trimethyl-silane 
• 173425-03-1 ethyl (2S)-2-<(tert-butyldiphenylsilyl)oxy>-3-methylbutanoate 
• 58479-61-1 tert-butylchlorodiphenylsilane 
• 63674-18-0 ethyl (2S)-2-hydroxy-3-methylbutanoate 
• 146861-20-3 (2S)-2-<(tert-butyldiphenylsilyl)oxy>-3-methylbutanal 
• 74-95-3 1,1-dibromomethane 

Downstream Products

• 143292-21-1 <2S,2(1S),3aR>-2-<1-<(tert-butyldiphenylsilyl)oxy>-2-methylpropyl>-3,3a,4,5,6,7-hexahydro-2H-isoxazolo<2,3-a>pyridine 
• 143264-48-6 <2R,2(1S),3aS>-2-<1-<(tert-butyldiphenylsilyl)oxy>-2-methylpropyl>-3,3a,4,5,6,7-hexahydro-2H-isoxazolo<2,3-a>pyridine 
• 173425-07-5 <2S,2(2R),2(3S)>-N-<(benzyloxy)carbonyl>-2-(2,3-dihydroxy-4-methylpentyl)piperidine 

Relevant academic research and scientific papers

Rhodium-catalyzed synthesis of terminal alkenes

Terminal alkenes have been efficiently prepared via a rhodium-catalyzed olefination procedure using Wilkinson's catalyst in the presence of triphenylphosphine, 2-propanol and trimethylsilyldiazomethane. Optimized reaction conditions are described for aldehydes and ketones, as well as alternative work up procedures. Georg Thieme Verlag Stuttgart.

Enantioselective total synthesis of the macrocyclic spermidine alkaloid (-)-oncinotine

The macrocyclic spermidine alkaloid (-)-oncinotine (1), isolated from Oncinotis nitida (Apocynaceae), was synthesized enantioselectively for the first time based on intramolecular iminium ion cyclization utilizing enantiomerically pure (2S)-N-[(benzyloxy)