143264-54-4 Usage
Uses
Used in Pharmaceutical Industry:
(S)-1-Cbz-2-(2-Oxoethyl)Piperidine is utilized as a chiral intermediate for the synthesis of various drug candidates. Its unique structure allows for the introduction of additional chemical moieties and the modification of pharmacological properties, enhancing the compound's therapeutic applications.
Used in Organic Synthesis:
In the realm of organic synthesis, (S)-1-Cbz-2-(2-Oxoethyl)Piperidine is employed as a building block for the construction of complex molecular entities. Its reactivity and structural features facilitate the creation of a diverse array of biologically active compounds with potential applications in medicine and other fields.
Used in Medicinal Chemistry:
(S)-1-Cbz-2-(2-Oxoethyl)Piperidine is leveraged in medicinal chemistry as a key component in the development of new pharmaceuticals. Its ability to be further functionalized makes it a valuable tool for the design and synthesis of molecules with specific therapeutic targets and improved efficacy.
Overall, (S)-1-Cbz-2-(2-Oxoethyl)Piperidine's multifaceted applications across different industries underscore its significance as a foundational compound in the advancement of pharmaceutical and chemical research.
Check Digit Verification of cas no
The CAS Registry Mumber 143264-54-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,4,3,2,6 and 4 respectively; the second part has 2 digits, 5 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 143264-54:
(8*1)+(7*4)+(6*3)+(5*2)+(4*6)+(3*4)+(2*5)+(1*4)=114
114 % 10 = 4
So 143264-54-4 is a valid CAS Registry Number.
143264-54-4Relevant academic research and scientific papers
Improved protocol for asymmetric, intramolecular heteroatom Michael addition using organocatalysis: Enantioselective syntheses of homoproline, pelletierine, and homopipecolic acid
Carlson, Erik C.,Rathbone, Lauren K.,Yang, Hua,Collett, Nathan D.,Carter, Rich G.
, p. 5155 - 5158 (2008/09/21)
(Chemical Equation Presented) An improved protocol for the construction of enantioenriched pyrrolidine, indoline, and piperidine rings using an organocatalyzed, intramolecular heteroatom Michael addition is described. Application to the enantioselective synthesis of homoproline, homopipecolic acid, and pelletierine has been accomplished.
Enantioselective total synthesis of the macrocyclic spermidine alkaloid (-)-oncinotine
Ina, Hiroji,Ito, Masayuki,Kibayashi, Chihiro
, p. 1023 - 1029 (2007/10/03)
The macrocyclic spermidine alkaloid (-)-oncinotine (1), isolated from Oncinotis nitida (Apocynaceae), was synthesized enantioselectively for the first time based on intramolecular iminium ion cyclization utilizing enantiomerically pure (2S)-N-[(benzyloxy)
Diastereofacial Selectivity in Intermolecular Nitrone Cycloadditions to Chiral Allyl Ethers. Application to Chiral Synthesis of Coniine
Ito, Masayuki,Maeda, Masae,Kibayashi, Chihiro
, p. 3765 - 3768 (2007/10/02)
The intermolecular cycloadditions of a cyclic nitrone to chiral allyl ethers take place with erythro selectivity, where the degree of selectivity achieved is dependent upon the size of the alkyl substituent attached to the allylic chiral center, and these reactions are applied to the synthesis of optically active alkaloid coniine.
