143264-59-9Relevant academic research and scientific papers
A Facile Synthesis of Disubstituted 1,1-Difluoro-1-alkenes via Double Transmetalation of 2,2-difluorovinylboranes
Ichikawa, Junji,Minami, Toru,Sonoda, Takaaki,Kobayashi, Hiroshi
, p. 3779 - 3782 (2007/10/02)
2,2,2-Trifluoroethyl p-toluenesulfonate is treated with butyllithium and trialkylboranes successively to generate 1-alkyl-2,2-difluorovinylboranes, which couple with aryl iodides in the presence of cuprous iodide and palladium catalyst to afford 1,1-difluoro-1-alkenes in excellent yields. Key Words: Difluoroalkene; Difluorovinylborane; Transmetalation; Coupling reaction; Palladium catalyst
A Novel Synthesis of Disubstituted 1,1-Difluoro-1-alkenes by Using 2,2,2-Trifluoroethyl p-Toluenesulfonate as a Difluorovinylidene Unit
Ichikawa, Junji,Moriya, Tsukasa,Sonoda, Takaaki,Kobayashi, Hiroshi
, p. 961 - 964 (2007/10/02)
2,2,2-Trifluoroethyl p-toluenesulfonate is treated with lithium diisopropylamide and trialkylboranes successively to generate 1-alkyl-2,2-difluorovinylboranes, which in turn couple with aryl iodides in the presence of palladium catalyst and tetrabutylammo
