1432655-48-5Relevant articles and documents
Regio- and stereoselective synthesis of 1-(1-halovinyl)-1H-indoles from 1-ethynyl-1H-indoles with in situ generated HX
Sato, Akihiro H.,Ohashi, Kazuhiro,Ito, Kouhei,Iwasawa, Tetsuo
, p. 2878 - 2881 (2013)
A facile approach to 1-(1-halovinyl)-1H-indoles from readily accessible 1-ethynyl-1H-indoles with in situ generated HX is described. The simple protocol enables a regio- and stereoselective hydrohalogenation to the triple bonds in gram-scale, and provides a general entry for novel N-alkenylindole derivatives.