1432669-51-6

Basic information

• Product Name: (R)-2-((2S,5R,6S)-2-(4-fluorobenzyl)-5,6-bis(4-chlorophenyl)-3-oxomorpholino)pentanoic acid
• Synonyms: (R)-2-((2S,5R,6S)-2-(4-fluorobenzyl)-5,6-bis(4-chlorophenyl)-3-oxomorpholino)pentanoic acid
• CAS NO: 1432669-51-6
• Molecular Weight: 530.423
• Mol File: 1432669-51-6.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: (R)-2-((2S,5R,6S)-2-(4-fluorobenzyl)-5,6-bis(4-chlorophenyl)-3-oxomorpholino)pentanoic acid(CAS DataBase Reference)
• NIST Chemistry Reference: (R)-2-((2S,5R,6S)-2-(4-fluorobenzyl)-5,6-bis(4-chlorophenyl)-3-oxomorpholino)pentanoic acid(1432669-51-6)
• EPA Substance Registry System: (R)-2-((2S,5R,6S)-2-(4-fluorobenzyl)-5,6-bis(4-chlorophenyl)-3-oxomorpholino)pentanoic acid(1432669-51-6)

Safety Data

• Hazardous Substances Data: 1432669-51-6(Hazardous Substances Data)

Upstream product

• 1432669-78-7 (R)-ethyl 2-((2S,3R)-2,3-bis(4-chlorophenyl)-5-oxomorpholino)pentanoate 
• 1432669-80-1 (R)-ethyl 2-((2S,5R,6S)-2-(4-fluorobenzyl)-5,6-bis(4-chlorophenyl)-3-oxomorpholino)pentanoate 
• 1432669-70-9 (±)-tert-butyl 1,2-Bis(4-chlorophenyl)-2-oxoethylcarbamate 
• 1239611-22-3 (±)-tert-butyl 1-(4-chlorophenyl)-2-(methoxy(methyl)amino)-2-oxoethylcarbamate 
• 53994-85-7 (±)-2-(tert-butoxycarbonyl)-2-(4-chlorophenyl)acetic Acid 
• 6212-33-5 2-(4-Chlorophenyl)glycine 
• 459-46-1 4-Fluorobenzyl bromide 

Relevant articles and documents

CIS-MORPHOLINONE AND OTHER COMPOUNDS AS MDM2 INHIBITORS FOR THE TREATMENT OF CANCER

The present invention provides MDM2 inhibitor compounds of Formula (I), or the pharmaceutically acceptable salts thereof, wherein the variables are defined above, which compounds are useful as therapeutic agents, particularly for the treatment of cancers. The present invention also relates to pharmaceutical compositions that contain an MDM2 inhibitor.