143288-21-5Relevant articles and documents
A versatile polypeptide platform for integrated recognition and reporting: Affinity arrays for protein-ligand interaction analysis
Enander, Karin,Dolphin, Gunnar T.,Liedberg, Bo,Lundstroem, Ingemar,Baltzer, Lars
, p. 2375 - 2385 (2007/10/03)
A molecular platform for protein detection and quantification is reported in which recognition has been integrated with direct monitoring of target-protein binding. The platform is based on a versatile 42-residue helix-loop-helix polypeptide that dimerize
Benzenesulfonamide-peptide conjugates as probes for secondary binding sites near the active site of carbonic anhydrase
Sigal, George B.,Whitesides, George M.
, p. 559 - 564 (2007/10/03)
Libraries of N-(4-sulfamoylbenzoyl)oligoglycines terminated with different L-amino acids were screened to identify tight binding inhibitors of human carbonic anhydrase II. Inhibitors terminated with hydrophobic amino acids showed significant enhancements in binding compared to the corresponding glycine derivatives. No enhancements were observed due to polar interactions.