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Usage

Uses

Used in Veterinary Medicine:
4-Hydrazino-2,6-dimethylpyrimidine is used as an antiprotozoal agent for the prevention and treatment of coccidiosis in animals, particularly poultry. It is effective in targeting the metabolic pathways of thiamine in coccidia, leading to their death and thus alleviating the disease.
Used in Poultry Industry:
In the poultry industry, 4-Hydrazino-2,6-dimethylpyrimidine is used as a prophylactic and therapeutic agent to control coccidiosis, ensuring the health and productivity of the poultry population. Its administration through medicated feed or water provides a convenient and effective means of disease management.

InChI:InChI=1/C9H12O/c1-2-9(10)8-6-4-3-5-7-8/h3-7,9-10H,2H2,1H3/t9-/m0/s1

Upstream product

• 4472-45-1 4-chloro-2,6-dimethylpyrimidine 
• 128381-47-5 1-(4-Chloro-phenyl)-ethanone O-(2,6-dimethyl-pyrimidin-4-yl)-oxime 

Downstream Products

• 1155702-82-1 C₁₄H₁₆N₄O₂ 
• 1155702-69-4 C₁₄H₁₆N₄ 
• 1155702-59-2 C₁₃H₁₃FN₄ 
• 1155702-62-7 C₁₃H₁₃ClN₄ 
• 187874-78-8 6-benzylidenehydrazino-2,4-dimethylpyrimidine 
• 1155702-71-8 C₁₄H₁₆N₄O 
• 1155702-79-6 C₁₃H₁₂Cl₂N₄ 
• 1155702-65-0 C₁₃H₁₃BrN₄ 
• 1155702-80-9 C₁₅H₁₈N₄O₂ 
• 1619900-24-1 2,4-dimethyl-6-[3-phenyl-5-(trifluoromethyl)-1H-pyrazol-1-yl]pyrimidine 
• 1619900-14-9 6-[3-(difluoromethyl)-5-phenyl-1H-pyrazol-1-yl]-2,4-dimethylpyrimidine 
• 1421923-85-4 C₁₉H₁₅F₆N₇O 
• 1338824-83-1 C₁₅H₁₈N₄O 
• 1338824-94-4 C₁₄H₁₅N₅O₂ 

Relevant academic research and scientific papers

CALPAIN MODULATORS AND THERAPEUTIC USES THEREOF

Disclosed herein are small molecule calpain modulator compositions, pharmaceutical compositions, the use and preparation thereof.

Synthesis, reactions and theoretical studied of triazolotriazolopyrazinium-3-aminides

Triazolopyrimidinium-3-aminides 5a-h have been synthesised by treatment pyridin-6-yl thiosemicarbazide derivatives 7f-n with dicyclohexylcarbodiimide (DCC).The above aminides 5a-h were slowly hydrolysed in water but very rapidly hydrolysed in 5 M aqueous hydrochloric acid to give substituted 1,2,4-triazole derivatives (e.g. 5a,d,g -> 8e,a,f, respectively); related nucleophilic ring-opening reactions occurred when the aminides (cf. 5a-h) were treated with (separately) methanol and ethanol (e.g. 5d->8c and 8d, respectively).A series of analogous triazolopyrazinium-3-aminides 6a-e was prepared following the procedures described above.The pyrazinium aminides 6 are stable in aq. 2 M HCl, and a stable hydrochloride salt 13 was formed from one such substrate 6a.

SYNTHESIS OF SUBSTITUTED METHYL ARYL KETONE PYRIMIDINYLOXIMES AND THEIR REACTIONS WITH NUCLEOPHILES

Chloropyrimidines react readily with the sodium salts of alkyl aryl ketoximes to give acetophenone O-(2,4-dimethylpyrimidin-6-yl)- and O-(4,6-dimethylpyrimidin-2-yl)oximes, the oximino-groups in which readily undergo nucleophilic substitution.