143329-58-2 Usage
Uses
Used in Pharmaceutical and Agrochemical Synthesis:
5-Bromo-[1,2,4]triazolo[1,5-a]pyridine is used as a key intermediate in the synthesis of various pharmaceuticals and agrochemicals, contributing to the development of new drugs and pesticides. Its unique structure allows for the creation of a wide range of biologically active compounds with potential therapeutic and pesticidal effects.
Used in Medicinal Chemistry Research:
In the field of medicinal chemistry, 5-Bromo-[1,2,4]triazolo[1,5-a]pyridine is employed as a building block for the design and synthesis of novel heterocyclic compounds with potential therapeutic applications. Its structural diversity and versatility make it a valuable tool for exploring new chemical space and discovering innovative drug candidates.
Used in Organic Synthesis as a Reagent:
5-Bromo-[1,2,4]triazolo[1,5-a]pyridine serves as a reagent in organic synthesis, facilitating various chemical reactions and transformations. Its presence can enhance the reactivity and selectivity of certain processes, making it a useful component in the synthesis of complex organic molecules.
Used in Chemical Research:
As a subject of research, 5-Bromo-[1,2,4]triazolo[1,5-a]pyridine is utilized to investigate its potential therapeutic properties and explore its applications in various chemical processes. This research contributes to the understanding of its chemical behavior and helps to unlock its full potential in various industries, including pharmaceuticals, agrochemicals, and materials science.
Check Digit Verification of cas no
The CAS Registry Mumber 143329-58-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,4,3,3,2 and 9 respectively; the second part has 2 digits, 5 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 143329-58:
(8*1)+(7*4)+(6*3)+(5*3)+(4*2)+(3*9)+(2*5)+(1*8)=122
122 % 10 = 2
So 143329-58-2 is a valid CAS Registry Number.
143329-58-2Relevant academic research and scientific papers
Novel urate anion transporter 1 (URAT1) inhibitors and application thereof in medicines
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Paragraph 0107; 0109-0111, (2017/11/04)
The invention discloses novel urate anion transporter 1 (URAT1) inhibitors and application thereof in medicines. The novel URAT1 inhibitors are compounds shown in a formula (I) and pharmacologically acceptable salts of the compounds, wherein Y or Z is respectively and independently selected from N or CH; R1 or R2 is respectively and independently selected from H, D, halogen, cyano, hydroxyl, carboxyl, C1-4 alkyl, substituted C1-4 alkyl, C3-4 cycloalkyl, C1-4 alkoxy, substituted C1-4 alkoxy, phenyl, substituted phenyl, heterocyclic aryl or substituted heterocyclic aryl; R3 or R4 is respectively and independently selected from H or C1-3 alkyl, or R3 and R4 form 3-6-membered cycloalkyl together; R5 is H, C1-4 alkyl or substituted C1-4 alkyl. The compounds provided by the invention can be applied to preparation of uric acid excretion promoting medicines, and are especially used for medicines for treating or preventing hyperuricemia or gout. The formula (I) is described in the description.
New method for the general synthesis of [1,2,4]triazolo[1,5-a]pyridines
Huntsman, Elliott,Balsells, Jaume
, p. 3761 - 3765 (2007/10/03)
[1,2,4]Triazolo[1,5-a]pyridines without substituants on the 2-position have been prepared from 2-aminopyridines by cyclization of N-(pyrid-2-yl) formamidoximes with trifluoroacetic anhydride. Triazoles substituted at any position on the pyridine ring may be prepared in good yields and under mild reaction conditions. Wiley-VCH Verlag GmbH & Co. KGaA, 2005.
