143329-58-2

Basic information

• Product Name: 5-BROMO-[1,2,4]TRIAZOLO[1,5-A]PYRIDINE
• Synonyms: 5-BROMO-[1,2,4]TRIAZOLO[1,5-A]PYRIDINE;[1,2,4]Triazolo[1,5-a]pyridine, 5-broMo-;5-BroMo[1,2,4]triazolo[1,...
• CAS NO: 143329-58-2
• Molecular Formula: C₆H₄BrN₃
• Molecular Weight: 198.02
• Product Categories: Building Blocks;Pyridine;Heterocycle-Pyridine series
• Mol File: 143329-58-2.mol
• Article Data: 3

Chemical Properties

• Melting Point: 145-150°C
• Appearance: /
• Density: 1.891 g/cm³
• PKA: 1.45±0.30(Predicted)
• CAS DataBase Reference: 5-BROMO-[1,2,4]TRIAZOLO[1,5-A]PYRIDINE(CAS DataBase Reference)
• NIST Chemistry Reference: 5-BROMO-[1,2,4]TRIAZOLO[1,5-A]PYRIDINE(143329-58-2)
• EPA Substance Registry System: 5-BROMO-[1,2,4]TRIAZOLO[1,5-A]PYRIDINE(143329-58-2)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26
• WGK Germany: 3
• Hazardous Substances Data: 143329-58-2(Hazardous Substances Data)

Usage

General Description

5-Bromo-[1,2,4]triazolo[1,5-a]pyridine is a chemical compound with the molecular formula C5H3BrN4. It is a heterocyclic organic compound that contains a five-membered ring with a nitrogen atom and a five-membered ring with a nitrogen and a sulfur atom. 5-BROMO-[1,2,4]TRIAZOLO[1,5-A]PYRIDINE is used in the synthesis of pharmaceuticals and agrochemicals, and has potential applications in the field of medicinal chemistry. It is also used as a building block in the synthesis of other heterocyclic compounds, and has been the subject of research for its potential therapeutic properties. Additionally, it is used as a reagent in organic synthesis and in chemical research.

Upstream product

• 19798-81-3 2-Amino-6-bromopyridine 
• 124-73-2 1,2-dibromo-1,1,2,2-tetrafluoroethane 
• 274-85-1 s-triazolo(1,5-a)pyridine 

Relevant articles and documents

Novel urate anion transporter 1 (URAT1) inhibitors and application thereof in medicines

The invention discloses novel urate anion transporter 1 (URAT1) inhibitors and application thereof in medicines. The novel URAT1 inhibitors are compounds shown in a formula (I) and pharmacologically acceptable salts of the compounds, wherein Y or Z is respectively and independently selected from N or CH; R1 or R2 is respectively and independently selected from H, D, halogen, cyano, hydroxyl, carboxyl, C1-4 alkyl, substituted C1-4 alkyl, C3-4 cycloalkyl, C1-4 alkoxy, substituted C1-4 alkoxy, phenyl, substituted phenyl, heterocyclic aryl or substituted heterocyclic aryl; R3 or R4 is respectively and independently selected from H or C1-3 alkyl, or R3 and R4 form 3-6-membered cycloalkyl together; R5 is H, C1-4 alkyl or substituted C1-4 alkyl. The compounds provided by the invention can be applied to preparation of uric acid excretion promoting medicines, and are especially used for medicines for treating or preventing hyperuricemia or gout. The formula (I) is described in the description.

Regioselective Lithiation and Reaction of Triazolopyridine and Pyrazolopyridine

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