143356-09-6

Basic information

• Product Name: 1H-INDENE-2-ACETIC ACID,2,3-DIHYDRO-,ETHYL ESTER
• Synonyms: 1H-INDENE-2-ACETIC ACID,2,3-DIHYDRO-,ETHYL ESTER;ethyl 2-(2,3-dihydro-1H-inden-2-yl)acetate
• CAS NO: 143356-09-6
• Molecular Formula: C13H16O2
• Molecular Weight: 204.26
• Mol File: 143356-09-6.mol
• Article Data: 6

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 1H-INDENE-2-ACETIC ACID,2,3-DIHYDRO-,ETHYL ESTER(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-INDENE-2-ACETIC ACID,2,3-DIHYDRO-,ETHYL ESTER(143356-09-6)
• EPA Substance Registry System: 1H-INDENE-2-ACETIC ACID,2,3-DIHYDRO-,ETHYL ESTER(143356-09-6)

Safety Data

• Hazardous Substances Data: 143356-09-6(Hazardous Substances Data)

Usage

Chemical classification

It is a chemical compound derived from 1H-indene.

Usage in industry

Commonly used in fragrance and flavoring industry.

Applications

Used as a flavoring agent in food products, a component of perfumes and scented products, and in the production of pharmaceuticals.

Potential properties

May have potential medicinal properties.

Odor

Has a sweet, floral odor.

Usage in fragrances and flavors

Often used to add a natural, fruity note.

Future applications

May have potential applications in the development of new pharmaceuticals or other products due to its chemical properties.

Upstream product

• 64-17-5 ethanol 
• 37868-26-1 2-(indan-2-yl)acetic acid 
• 867-13-0 diethoxyphosphoryl-acetic acid ethyl ester 
• 615-13-4 2-indanone 
• 623-73-4 diazoacetic acid ethyl ester 
• 95-13-6 1-indene 
• 157406-12-7 (E)-2-(1-oxo-1,3-dihydro-2H-inden-2-ylidene)acetic acid 
• 114915-75-2 1-oxoindan-Δ^2,α-acetic acid 
• 83-33-0 inden-1-one 

Downstream Products

• 159011-42-4 1-bromo-2-(2-indanyl)ethane 
• 772-28-1 2-(indan-2-yl)ethanol 

Relevant articles and documents

Radical-Mediated Strategies for the Functionalization of Alkenes with Diazo Compounds

One of the most common reactions of diazo compounds with alkenes is cyclopropanation, which occurs through metal carbene or free carbene intermediates. Alternative functionalization of alkenes with diazo compounds is limited, and a methodology for the addition of the elements of Z-CHR2 (with Z = H or heteroatom, and CHR2 originates from N2 CR2) across a carbon-carbon double bond has not been reported. Here we report a novel reaction of diazo compounds utilizing a radical-mediated addition strategy to achieve difunctionalization of diverse alkenes. Diazo compounds are transformed to carbon radicals with a photocatalyst or an iron catalyst through PCET processes. The carbon radical selectively adds to diverse alkenes, delivering new carbon radical species, and then forms products through hydroalkylation by thiol-assisted hydrogen atom transfer (HAT), or forms azidoalkylation products through an iron catalytic cycle. These two processes are highly complementary, proceed under mild reaction conditions, and show high functional group tolerance. Furthermore, both transformations are successfully performed on a gram-scale, and diverse γ-amino esters, γ-amino alcohols, and complex spirolactams are easily prepared with commercially available reagents. Mechanistic studies reveal the plausible pathways that link the two processes and explain the unique advantages of each.

TRICYCLIC 1,2,4-TRIAZINE OXIDES AND COMPOSITIONS THEREFROM FOR THERAPEUTIC USE IN CANCER TREATMENTS

The invention relates to novel tricyclic 1,2,4-triazine-1-oxides and novel tricyclic 1,2,4-triazine-1,4-dioxides of formula: (I); and to related analogues, to their preparation, and to their use as hypoxia-selective drugs and radiosensitizers for cancer therapy, both alone or in combination with radiation and/or other anticancer drugs.

FUSED POLYCYCLIC AMINO ACIDS AS PHARMACEUTICAL AGENTS

A novel series of amino acids of Formula (I) or a pharmaceutically acceptable salt thereof.