143360-01-4

Basic information

• Product Name: N-(4-BROMO-2-METHOXY-PHENYL)-ACETAMIDE
• Synonyms: CHEMBRDG-BB 7258803;N-(4-BROMO-2-METHOXY-PHENYL)-ACETAMIDE;N-(4-bromo-2-methoxyphenyl)acetamide(SALTDATA: FREE)
• CAS NO: 143360-01-4
• Molecular Formula: C₉H₁₀BrNO₂
• Molecular Weight: 244.09
• Mol File: 143360-01-4.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 343.8°Cat760mmHg
• Flash Point: 161.7°C
• Appearance: /
• Density: 1.5g/cm³
• Vapor Pressure: 6.89E-05mmHg at 25°C
• Refractive Index: 1.589
• Storage Temp.: Sealed in dry,Room Temperature
• CAS DataBase Reference: N-(4-BROMO-2-METHOXY-PHENYL)-ACETAMIDE(CAS DataBase Reference)
• NIST Chemistry Reference: N-(4-BROMO-2-METHOXY-PHENYL)-ACETAMIDE(143360-01-4)
• EPA Substance Registry System: N-(4-BROMO-2-METHOXY-PHENYL)-ACETAMIDE(143360-01-4)

Safety Data

• Hazardous Substances Data: 143360-01-4(Hazardous Substances Data)

Usage

General Description

N-(4-Bromo-2-methoxy-phenyl)-acetamide, also known as Bromoacetyl-4-ethoxyaniline, is an organic compound with the molecular formula C10H12BrNO2. It is a white to off-white crystalline powder that is soluble in organic solvents such as ethanol and methanol. This chemical is often used as an intermediate in the synthesis of pharmaceuticals and other organic compounds. It is also employed in the manufacture of dyes, pigments, and other chemical products. N-(4-Bromo-2-methoxy-phenyl)-acetamide may also have applications in research and development, particularly in the fields of organic chemistry and medicinal chemistry. However, it is important to handle this compound with care as it may pose health and environmental hazards.

InChI:InChI=1/C9H10BrNO2/c1-6(12)11-8-4-3-7(10)5-9(8)13-2/h3-5H,1-2H3,(H,11,12)

Upstream product

• 93-26-5 2-methoxyacetanilide 
• 16394-40-4 N-(4-bromo-2-hydroxyphenyl)acetamide 
• 77-78-1 dimethyl sulfate 
• 59557-91-4 4-bromo-2-methoxyaniline 
• 108-24-7 acetic anhydride 

Downstream Products

• 1307885-41-1 N-(4-(7-(3-fluoro-4-methoxyphenyl)-1,3-dimethyl-2,6-dioxo-2,3,6,7-tetrahydro-1H-purin-8-yl)-2-methoxyphenyl)acetamide 
• 1034617-72-5 N-[2-methoxy-4-(4-methylpiperazin-1-yl)phenyl]acetamide 

Relevant articles and documents

A para-C–H Functionalization of Aniline Derivatives via In situ Generated Bulky Hypervalent Iodinium Reagents

A practical para-C-H functionalization of aniline derivatives has been developed using an in situ generated bulky hypervalent iodinium reagent. Para-iodo, bromo, chloro, nitro, trifluormethyl aniline derivatives can be obtained efficiently, in many cases in 10 min in a transition metal-free manner. Medicinal chemicals or intermediates can be purified without column chromatography or recrystallization, which significantly reduces the waste and simplifies the work-up process.

SUBSTITUTED PYRAZOLO-QUINAZOLINE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND THEIR USE AS KINASE INHIBITORS

Pyrazolo-quinazoline derivatives of formula (I) as defined in the specification, and pharmaceutically acceptable salts thereof, process for their preparation and pharmaceutical compositions comprising them are disclosed; the compounds of the invention may

Reexamination of the Thermolytic Rearrangement of 4-Halophenyl Azides to 2-Aminophenols and other Products

The halogenation of derivatives of 2-aminophenol with N-chloro- and N-bromosuccinimides at ambient temperatures in acetic acid was studied.With the necessary compounds available, a reexamination of the thermolytic rearrangement of 2-halophenyl azides to 2-aminophenols and other products was undertaken.It is certain that the rearrangement of 4-halophenyl azides to 2-aminophenols occurs but the products identified in this study differ significantly from those reported previously by Suschitzky et al. (1963, 1966). Keywords: Acetylated-2-amino-5-halophenols; 2-Acetamido-5-haloanisoles; 6-Halo-2-methylbenzoxazoles; 6-Halobenzoxazolones; 6-Halotriacetylaminophenols; 1H-NMR spectra; Fungicidal activity.