143377-87-1

Upstream product

• 58479-61-1 tert-butylchlorodiphenylsilane 
• 143378-37-4 2-(3,4-dimethoxyphenyl)-1-phenyl-2-(tert-butyldiphenylsilyloxy)ethylamine 
• 143378-39-6 N-<2-(3,4-dimethoxyphenyl)-1-phenyl-2-(tert-butyldiphenylsilyloxy)ethyl>acetamide 
• 143378-36-3 2-(3,4-dimethoxyphenyl)-2-(tert-butyldiphenylsilyloxy)acetonitrile 
• 6309-18-8 2-(3,4-dimethoxyphenyl)-2-hydroxyacetonitrile 
• 143378-41-0 (3S*,4R*)-6,7-dimethoxy-1-methyl-3-phenyl-4-(tert-butyldiphenylsilyloxy)-3,4-dihydroisoquinoline 

Downstream Products

• 143378-44-3 (1S*,3S*,4R*)-6,7-dimethoxy-4-hydroxy-1-methyl-3-phenyltetrahydroisoquinoline 
• 143378-44-3 (1R*,3S*,4R*)-6,7-dimethoxy-4-hydroxy-1-methyl-3-phenyltetrahydroisoquinoline 

Relevant academic research and scientific papers

(1R*,3R*,4S*)-4-(tert-butyldiphenylsilyloxy)-6,7- dimethoxy-1-methyl-3-phenyl-1,2,3,4-tetrahydroisoquinoline

Ambiguous information obtained from 1H NMR spectroscopy has prompted an investigation of the correct stereochemistry of the title compound, C34H39NO3Si, by X-ray diffraction analysis. An uncommon pseudoaxial-axi

Silicon-mediated isoquinoline synthesis: Preparation and stereochemical characterization of 4-hydroxy-3-phenylisoquinolines

The silicon-mediated synthesis of 4-hydroxy-6,7-dimethoxy-3-phenylisoquinoline derivatives is reported. The described procedure implies synthetically useful yields and a high degree of stereoselectivity.