6309-18-8

Basic information

• Product Name: Veratraldehyde cyanohydrin
• Synonyms: Veratraldehyde cyanohydrin
• CAS NO: 6309-18-8
• Molecular Formula: C₁₀H₁₁NO₃
• Molecular Weight: 193.2
• Mol File: 6309-18-8.mol
• Article Data: 21

Chemical Properties

• Melting Point: 104-105 °C
• Boiling Point: 356.8°C at 760 mmHg
• Flash Point: 169.6°C
• Appearance: /
• Density: 1.193g/cm³
• Vapor Pressure: 1.04E-05mmHg at 25°C
• Refractive Index: 1.537
• PKA: 10.32±0.20(Predicted)
• CAS DataBase Reference: Veratraldehyde cyanohydrin(CAS DataBase Reference)
• NIST Chemistry Reference: Veratraldehyde cyanohydrin(6309-18-8)
• EPA Substance Registry System: Veratraldehyde cyanohydrin(6309-18-8)

Safety Data

• Hazardous Substances Data: 6309-18-8(Hazardous Substances Data)

Usage

InChI:InChI=1/C10H11NO3/c1-13-9-4-3-7(8(12)6-11)5-10(9)14-2/h3-5,8,12H,1-2H3

Upstream product

• 74-90-8 hydrogen cyanide 
• 120-14-9 3,4-dimethoxy-benzaldehyde 
• 151-50-8 potassium cyanide 
• 68413-92-3 sodium (3,4-dimethoxyphenyl)(hydroxy)methanesulfonate 
• 613-90-1 benzoyl cyanide 
• 143-33-9 sodium cyanide 
• 95392-01-1 2-(3,4-dimethoxyphenyl)-2-((trimethylsilyl)oxy)acetonitrile 
• 7677-24-9 trimethylsilyl cyanide 
• 2033-89-8 3,4-dimethoxyphenol 

Downstream Products

• 143378-36-3 2-(3,4-dimethoxyphenyl)-2-(tert-butyldiphenylsilyloxy)acetonitrile 
• 102-32-9 3,4-dihydroxyphenylacetate 
• 13443-54-4 3,4-dimethoxyphenylglycolic acid 
• 2911-73-1 α-hydroxy-3,4-dimethoxyphenylacetic acid methyl ester 
• 900175-68-0 benzyl 2-(3,4-dimethoxyphenyl)-2-hydroxyacetate 
• 900175-69-1 benzyl 2-chloro-2-(3,4-dimethoxyphenyl)acetate 
• 94582-71-5 C₁₁H₁₅NO₄*ClH 
• 5653-66-7 1-(3,4-dimethoxyphenyl)-2-(methylamino)ethan-1-ol 
• 54837-87-5 [2-(3,4-Dimethoxy-phenyl)-2-hydroxy-ethyl]-carbamic acid ethyl ester 
• 3865-99-4 5-(3,4-dimethoxy-phenyl)-4,5-dihydro-oxazol-2-ylamine 
• 2656-10-2 erythro-2-amino-1-(3,4-dimethoxyphenyl)propan-1-ol 
• 2656-10-2 threo-2-amino-1-(3,4-dimethoxyphenyl)propan-1-ol 
• 143377-87-1 (1S*,3S*,4R*)-6,7-dimethoxy-1-methyl-3-phenyl-4-(tert-butyldiphenylsilyloxy)tetrahydroisoquinoline 
• 143377-87-1 (1R*,3S*,4R*)-4-(tert-butyldiphenylsilyloxy)-6,7-dimethoxy-1-methyl-3-phenyl-1,2,3,4-tetrahydroisoquinoline 

Relevant articles and documents

One-pot access to 2-amino-3-arylbenzofurans: Direct entry to polyheterocyclic chemical space

As a means to make new benzofuran-embedded polycyclic structures, we established two efficient one-pot sequential coupling routes to 2-amino-3-arylbenzofurans and 2-amino-3-arylnaphtho[2,1-b]furans. Further ring formation (six- and seven-membered rings) with the resulting amine moiety at the C2 position of benzofurans was realized, leading to further expansion of benzofuran-based chemical space.

2-(ARYLOXY)ACETAMIDE FACTOR VIIA INHIBITORS USEFUL AS ANTICOAGULANTS

The present invention relates generally to novel 2-(aryloxy)acetamides of Formula (I) or stereoisomers, tautomers, pharmaceutically acceptable salts, solvates, or prodrugs thereof, wherein the variables W, Y, Z, R7, R8, and R9 are as defined herein. These compounds are selective inhibitors of the serine protease coagulation factor VIIa which can be used as medicaments.

A new (R)-hydroxynitrile lyase from Prunus mume: Asymmetric synthesis of cyanohydrins

A new hydroxynitrile lyase (HNL) was isolated from the seed of Japanese apricot (Prunus mume). The enzyme has similar properties with HNL isolated from other Prunus species and is FAD containing enzyme. It accepts a large number of unnatural substrates (benzaldehyde and its variant) for the addition of HCN to produce the corresponding cyanohydrins in excellent optical and chemical yields. A new HPLC based enantioselective assay technique was developed for the enzyme, which promotes the addition of KCN to benzaldehyde in a buffered solution (pH=4.5).