1433884-42-4

Basic information

• Product Name: 2-benzyl-9-methyl-β-carbolinium bromide
• Synonyms: 2-benzyl-9-methyl-β-carbolinium bromide
• CAS NO: 1433884-42-4
• Molecular Weight: 353.261
• Mol File: 1433884-42-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-benzyl-9-methyl-β-carbolinium bromide(CAS DataBase Reference)
• NIST Chemistry Reference: 2-benzyl-9-methyl-β-carbolinium bromide(1433884-42-4)
• EPA Substance Registry System: 2-benzyl-9-methyl-β-carbolinium bromide(1433884-42-4)

Safety Data

• Hazardous Substances Data: 1433884-42-4(Hazardous Substances Data)

Upstream product

• 2521-07-5 9-methylnorharmane 
• 100-39-0 benzyl bromide 
• 244-63-3 betacarboline 

Relevant articles and documents

Synthesis and structure-activity relationships of N2-alkylated quaternary β-carbolines as novel antitumor agents

A series of novel N2-alkylated quaternary β-carbolines was synthesized by modification of position-1, 2, 7 and 9 of β-carboline nucleus with various alkyl and arylated alkyl substituents, and their cytotoxic activities in vitro and antitumor potencies in mice were evaluated. Compound 3m was found to be the most potent antitumor agent. SARs analysis revealed that (1) the substituents in position-2 and 9 of β-carboline nucleus played a vital role in modulation of antitumor activity; (2) the benzyl and 3-phenylpropyl substituents in position-2 and 9 of β-carboline ring were the optimal substituents giving rise to significant antitumor agent. These compounds might be a novel promising class of antitumor agents with clinical development potential.