143393-84-4Relevant academic research and scientific papers
Synthesis and biological activity of the D-3-deoxy-3-fluoro and D-3-chloro-3-deoxy analogues of phosphatidylinositol
Kozikowski,Powis,Fauq,Tuckmantel,Gallegos
, p. 963 - 971 (2007/10/02)
The naturally occurring inositol derivative, L-quebrachitol (1), serves as starting material for the synthesis of D-3-deoxy-3-fluoro- and D-3-chloro-3-deoxy-myo-inositol (4, 28). Their transformation into the title compounds 22 and 40 (abbreviated as FPI
Synthesis and evaluation of 3-modified 1D-myo-inositols as inhibitors and substrates of phosphatidylinositol synthase and inhibitors of myo-inositol uptake by cells
Johnson,Dahl,Shih,Schedler,Anderson,Benjamin,Baker
, p. 3628 - 3635 (2007/10/02)
A number of 3-substituted 1D-myo-inositols were synthesized and evaluated as substrates for phosphatidylinositol synthase and uptake by intact cells. 1D-3-Amino-, -3-chloro-, and -3-(acetylthio)-3-deoxy-myo-inositols were all synthesized by nucleophilic d
