6848-53-9Relevant academic research and scientific papers
Improved synthesis of dicyclohexylidene protected quebrachitol and its use in the synthesis of l-chiro-inositol derivatives
Baars, Sylvia M.,Hoberg, John O.
, p. 1680 - 1684 (2007/10/03)
A modified synthesis of 1l-1,2:3,4-di-O-cyclohexylidene-5-O-methyl-chiro-inositol has been accomplished that improves the overall procedure, yield, and environmental aspects of its formation. Several inositol analogues have been prepared from this intermediate for testing as biosynthetic inhibitors of glycosyl-phosphatidylinositol (GPI) anchor formation.
Enzyme-catalysed synthesis of galactosylated 1D- and 1L-chiro-inositol, 1D-pinitol, myo-inositol and selected derivatives using the β-galactosidase from the thermophile Thermoanaerobacter sp. strain TP6-B1
Hart, Joanne B.,Kroeger, Lars,Falshaw, Andrew,Falshaw, Ruth,Farkas, Erzsebet,Thiem, Joachim,Win, Anna L.
, p. 1857 - 1871 (2007/10/03)
The products from the enzymatic β-D-galactopyranosylation of 1D-chiro-inositol, 1D-pinitol, 1D-3-O-allyl-4-O-methyl-chiro-inositol, 1D-3,4-di-O-methyl-chiro-inositol, 1L-chiro-inositol and myo-inositol in combined yields ranging from 46% to 64% have been
Total synthesis of (-)-ovalicin and analogues from L-quebrachitol
Barton, Derek H. R.,Bath, Sophie,Billington, David C.,Gero, Stephan D.,Quiclet-Sire, Beatrice,Samadi, Mohammad
, p. 1551 - 1558 (2007/10/02)
We describe here the first chiral total synthesis of (-)-ovalicin and the synthesis of several related analogues, from the naturally occuring cyclitol L-quebrachitol.
Synthesis and evaluation of 3-modified 1D-myo-inositols as inhibitors and substrates of phosphatidylinositol synthase and inhibitors of myo-inositol uptake by cells
Johnson,Dahl,Shih,Schedler,Anderson,Benjamin,Baker
, p. 3628 - 3635 (2007/10/02)
A number of 3-substituted 1D-myo-inositols were synthesized and evaluated as substrates for phosphatidylinositol synthase and uptake by intact cells. 1D-3-Amino-, -3-chloro-, and -3-(acetylthio)-3-deoxy-myo-inositols were all synthesized by nucleophilic d
