1434152-98-3

Basic information

• Product Name: 1-(4-nitrophenyl)-4-phenoxy-2-phenyl-3H-pyrrolo[3,2,1-de]acridin-3-one
• CAS NO: 1434152-98-3
• Molecular Weight: 508.533
• Mol File: 1434152-98-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 1-(4-nitrophenyl)-4-phenoxy-2-phenyl-3H-pyrrolo[3,2,1-de]acridin-3-one(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(4-nitrophenyl)-4-phenoxy-2-phenyl-3H-pyrrolo[3,2,1-de]acridin-3-one(1434152-98-3)
• EPA Substance Registry System: 1-(4-nitrophenyl)-4-phenoxy-2-phenyl-3H-pyrrolo[3,2,1-de]acridin-3-one(1434152-98-3)

Safety Data

• Hazardous Substances Data: 1434152-98-3(Hazardous Substances Data)

Upstream product

• 1942-30-9 4-(phenylethynyl)nitrobenzene 
• 1434153-15-7 4-iodo-1-methoxy-3-(phenoxymethyl)-1H-pyrano[4,3-b]quinoline 

Relevant articles and documents

Tandem synthesis of pyrroloacridones via [3 + 2] alkyne annulation/ring-opening with concomitant intramolecular aldol condensation

An efficient cascade strategy for the direct synthesis of pyrrolo[3,2,1-de]acridones 4a-v, 5a-h from iodo-pyranoquinolines 2a-i by the palladium-catalyzed regioselective [3 + 2] alkyne annulation/ring-opening followed by intramolecular aldol condensation under microwave irradiation is described. The chemistry involves the in situ formation of pyrroloquinolines Y, via palladium-catalyzed selective [3 + 2] annulation of iodopyranoquinolines and internal akynes with ring-opening and successive intramolecular cross-aldol condensation. Both the symmetrical and unsymmetrical internal alkynes were reacted smoothly to provide the desired pyrroloacridones in good yields. This methodology provides the facile conversion of easily accessble iodopyranoquinoline into highly functionalized biologically important pyrroloacridones in a single process.