1942-30-9

Usage

Uses

Used in Organic Synthesis:
1-Nitro-4-phenylethynyl-benzene is used as a building block in organic synthesis for the creation of various other chemicals. Its versatile structure allows for the development of a range of chemical products.
Used in Pharmaceutical Preparation:
In the pharmaceutical industry, 1-Nitro-4-phenylethynyl-benzene is utilized in the preparation of pharmaceuticals. Its unique properties contribute to the development of new drugs with potential therapeutic applications.
Used in Dye and Pigment Production:
1-NITRO-4-PHENYLETHYNYL-BENZENE also finds application in the production of dyes and pigments, where its chemical characteristics are harnessed to create a spectrum of colorants for various industries.
Used in Medicinal Chemistry:
Due to its unique chemical structure, 1-Nitro-4-phenylethynyl-benzene has potential applications in medicinal chemistry, where it may contribute to the discovery and synthesis of novel therapeutic agents.
Used in Material Science:
Its reactivity and structural attributes also make 1-Nitro-4-phenylethynyl-benzene a candidate for material science applications, potentially leading to advancements in material development and technology.
It is crucial to handle and store 1-Nitro-4-phenylethynyl-benzene with care due to its potential health and environmental hazards if mismanaged.

Upstream product

• 636-98-6 p-nitrobenzene iodide 
• 201230-82-2 carbon monoxide 
• 1199-95-7 1-(trimethylstannyl)-2-phenylethyne 
• 33377-47-8 (4-nitrophenyl)Pd(P(C₆H₅)3)2I 
• 536-74-3 phenylacetylene 
• 1694-20-8 trans-4-nitrostilbene 
• 140-29-4 phenylacetonitrile 
• 317337-41-0 1-Nitro-4-(1,1,2,2-tetrabromo-2-phenyl-ethyl)-benzene 
• 100-00-5 4-chlorobenzonitrile 
• 32584-71-7 diphenyl(phenylethynyl)stibine 
• 126472-97-7 12-phenylethynyl-N-methyl-5,6,7,12-tetrahydrodibenz[c,f][1,5]azastibocine 
• 904689-35-6 12-phenylethynyl-N-t-butyl-5,6,7,12-tetrahydrodibenz[c,f][1,5]azastibocine 
• 586-78-7 para-nitrophenyl bromide 
• 123-75-1 pyrrolidine 

Downstream Products

• 131202-87-4 1-Methyl-2-(4-nitro-phenyl)-3-phenyl-1H-1-aza-phenalene 
• 131202-78-3 1-Methyl-3-(4-nitro-phenyl)-2-phenyl-1H-1-aza-phenalene 
• 13024-49-2 4-aminodibenzyl 
• 1849-25-8 4-phenylethynylphenylamine 
• 834-24-2 4-[(1Z)-2-phenylethenyl]benzeneamine 
• 1694-20-8 trans-4-nitrostilbene 
• 6624-53-9 (Z)-1-nitro-4-(2-phenylethenyl)-benzene 
• 1236115-73-3 methyl 2-(1-acetyl-4-phenyl-5-(4-nitrophenyl)-1H-pyrrol-2-yl)ethanoate 
• 1236115-72-2 methyl 2-(1-acetyl-4-(4-nitrophenyl)-5-phenyl-1H-pyrrol-2-yl)ethanoate 
• 1240052-20-3 C₂₇H₁₉NO₂ 
• 1741-96-4 2-phenyl-3-(p-nitrophenyl)-1H-indole 
• 1507357-39-2 2-(4-nitrophenyl)-3-phenyl-1H-indole 

Relevant academic research and scientific papers

Improved Sonogashira C-C coupling through clay supported palladium complexes with tridentate pincer bis-carbene ligands

Highly active recyclable Pd catalysts modified with a rigid C,N,C-tridentate pincer carbene ligand were successfully applied to the coupling of aryl halides with terminal acetylenes. The immobilization of Pd(II) complexes onto clays has beneficial effects

Highly active thiol-functionalized SBA-15 supported palladium catalyst for Sonogashira and Suzuki-Miyaura cross-coupling reactions

Highly ordered mesoporous silica SBA-15 with pendent 3-mercaptopropyl groups has been prepared by condensation of surface silanols and (3-mercaptopropyl)trimethoxysilane. Treatment of the mercaptopropylated SBA-15 with (CH3CN)2PdCl2 gave a heterogeneous Pd-catalyst. The immobilized Pd-catalyst served as an efficient heterogeneous catalyst for Sonogashira and Suzuki-Miyaura cross coupling reactions of aryl halides. Furthermore, the SBA-15 supported Pd-catalyst was recovered by a simple filtration from the reaction mixture and reused five times without significant loss of its catalytic activity. This journal is

Water-medium organic reactions catalyzed by active and reusable Pd/Y Heterobimetal-organic framework

A Pd/Y heterobimetallic MOF (denoted as Pd/Y-MOF) catalyst is synthesized by coordination of Pd(II) and Y(III) with 2,2′-bipyridine-5,5′- dicarboxylate acid (bpydc) under microwave irradiation condition and is characterized by XRD Rietveld refinement, FTIR, Raman, TG-DTA, and XPS. It is shown that the 3D extended framework is constructed by linking Pd(bpydc)Cl 2 building blocks via Y(III) coordinating to carboxylic groups. Pd/Y-MOF exhibits higher catalytic activity than Pd(bpydc)Cl2 in Suzuki-Miyaura coupling reaction and Sonogashira reaction owing to the highly dispersed Pd(II) sites in the layered structure of Pd/Y-MOF and the cooperative effect between Pd(II) and Y(III). The heterogeneity studies provide mechanistic evidence that the reaction proceeds on the surface of Pd(II) ions in the crystal framework. Thus, Pd/Y-MOF exhibits impressive size selectivity toward substrates. With the small-sized reactants, it displays comparable activities with Pd(OAc)2 homogeneous catalyst. However, extremely poor activity in Suzuki-Miyaura coupling reaction with bulk substrates 1-iodonaphthalene and 4-(tert-butyl) iodobenzene is observed due to the inhibition of diffusion into the micropore channels. In addition, Pd/Y-MOF can be easily recycled and reused owing to the high stability of the framework formed by coordination of Y(III) with carboxylic group. The incorporation of Pd(II) into the crystal framework of Pd/Y-MOF prohibits the leaching of Pd(II) active species.

Synthesis and characterization of mesoporous Pd(II) organometal nanoplatelet catalyst for copper-free Sonogashira reaction in water

Periodic mesoporous organopalladium(II)-bridged silica with platelet morphology (Pd(II)-PMO-P) was synthesized by the co-condensation of TEOS and Pd[PPh2(CH2)2Si(OC2H5)3]2Cl

Effect of addition of iron on morphology and catalytic activity of PdCu nanoalloy thin film as catalyst in Sonogashira coupling reaction

Palladium-supported catalysts are complex assemblies with a challenging preparation. Minor changes in their preparation conditions can affect the activity, selectivity and lifetime of these catalysts. PdCuFe nanoparticle (NP) thin films were supported on

Pd embedded in chitosan microspheres as tunable soft-materials for Sonogashira cross-coupling in water-ethanol mixture

Easy shaping of chitosan (CS) as porous self-standing nanofibrillar microspheres allows their use as a palladium carrier. Amino-groups on CS enable the modulation of Pd coordination, giving rise to three different support-catalyst interactions: weakly-coo

Self-Generation of Surface Roughness by Low-Surface-Energy Alkyl Chains for Highly Stable Superhydrophobic/Superoleophilic MOFs with Multiple Functionalities

We transformed the hydrophilic metal–organic framework (MOF) UiO-67 into hydrophobic UiO-67-Rs (R=alkyl) by introducing alkyl chains into organic linkers, which not only protected hydrophilic Zr6O8 clusters to make the MOF interspace

Preparation and catalytic properties of the triphenylarsine and triphenylstibine-stabilized tri-heteroleptic NHC–Pd?allyl complexes

A series of triphenylarsine and triphenylstibine-stabilized tri-heteroleptic NHC–Pd?allyl complexes were synthesized and characterized. The solid-state structures of the complexes shown mononuclear carbene palladium complexes, in which, each palladium cen

An efficient protocol for copper- and amine-free Sonogashira reactions catalyzed by mononuclear palladacycle complexes containing bidentate phosphine ligands

An efficient protocol for copper- and amine-free Sonogashira coupling of aryl halides with phenylacetylene in mild reaction conditions under air is reported using moisture/air-stable and robust palladacycle phosphine complexes as catalyst precursors. The use of 0.001 mol% catalysts in the presence of Cs2CO3 allows the coupling reaction to proceed with moderate to good yields. Also, 31P NMR studies showed that palladacycle 1 can be reduced to zerovalent palladium in methanol, by forming dppe dioxide.

A tyrosine-rich peptide induced flower-like palladium nanostructure and its catalytic activity

A specifically designed peptide, Tyr-Tyr-Ala-His-Ala-Tyr-Tyr (YYAHAYY), induced the formation of a flower-like palladium (Pd) nanostructure by controlling the size and shape of nanoparticles (NPs). The flower-shaped Pd NPs showed excellent catalytic activ