143438-91-9 Usage
General Description
3-Amino-3-[3-(trifluoromethyl)phenyl]propanoic acid is a chemical compound with the molecular formula C10H12F3NO2. It is an amino acid derivative with a trifluoromethylphenyl group attached to the third carbon atom of the propanoic acid chain. 3-Amino-3-[3-(trifluoromethyl)phenyl]propanoic acid has various applications in the field of medicinal chemistry, particularly in the development of drugs targeting neurological and psychiatric disorders. It has been studied as a potential antagonist of the glutamate receptors, which are involved in the pathophysiology of schizophrenia and other mental illnesses. Additionally, its unique chemical structure and properties make it a valuable building block for the synthesis of diverse organic compounds for pharmaceutical and agrochemical purposes.
Check Digit Verification of cas no
The CAS Registry Mumber 143438-91-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,4,3,4,3 and 8 respectively; the second part has 2 digits, 9 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 143438-91:
(8*1)+(7*4)+(6*3)+(5*4)+(4*3)+(3*8)+(2*9)+(1*1)=129
129 % 10 = 9
So 143438-91-9 is a valid CAS Registry Number.
InChI:InChI=1/C10H10F3NO2/c11-10(12,13)7-3-1-2-6(4-7)8(14)5-9(15)16/h1-4,8H,5,14H2,(H,15,16)
143438-91-9Relevant articles and documents
Iridium-catalysed C-H borylation of β-aryl-aminopropionic acids
MacDonald, Simon J. F.,Nortcliffe, Andrew,Robinson, Henry,Simelis, Klemensas,Stillibrand, Joe
supporting information, p. 6696 - 6701 (2020/09/21)
Iridium-catalysed catalytic, regioselective C-H borylation of β-aryl-aminopropionic acid derivatives gives access to 3,5-functionalised protected β-aryl-aminopropionic acid boronates. The synthetic versatility of these new boronates is demonstrated through sequential one-pot functionalisation reactions to give diverse building blocks for medicinal chemistry. The C-H borylation is also effective for dipeptide substrates. We have exemplified this methodology in the synthesis of a pan αv integrin antagonist.
BENZIMIDAZOLE DERIVATIVES USEFUL AS POTASSIUM CHANNEL INHIBITORS
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Page/Page column 61, (2019/03/12)
The present invention relates to compounds of the general formula (I). The compounds of formula I are potassium channel inhibitors useful for treatment of a cardiac disease, disorder or condition in a mammal.
NOVEL POTASSIUM CHANNEL INHIBITORS
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Page/Page column 65, (2017/09/15)
The present invention relates to a compound of the general formula (I). The compounds of formula (I) are useful for treatment of a cardiac disease, disorder or condition in a mammal.
