143446-15-5Relevant academic research and scientific papers
General method for the synthesis of 5-arylpyrrole-2-carboxylic acids
Ezquerra, Jesus,Pedregal, Concepcion,Rubio, Almudena,Valenciano, Jesus,Garcia Navio, Jose Luis,Alvarez-Builla, Julio,Vaquero, Juan Jose
, p. 6317 - 6320 (2007/10/02)
5-Arylpyrrole-2-carboxylic acids are prepared by DDQ oxidative aromatization of the corresponding ethyl 2-aryl-Δ1-pyrroline-5-carboxylate followed by basic hydrolysis.
An Efficient, Regiocontrolled Synthesis of 5-Aryl-2-carbethoxypyrroles from 3-Aryl-3-chloropropeniminium Salts
Gupton, John T.,Krolikowski, Dale A.,Yu, Richard H.,Vu, Phong,Sirkorski, James A.,et al.
, p. 5480 - 5483 (2007/10/02)
A variety of 3-aryl-3-chloropropeniminium salts react with α-amino acid esters under basic conditions to produce 2-carbethoxy-5-arylpyrroles in a regioselective manner.The overall process represents a short, efficient, and convergent synthesis of 2,5-disu
