143465-47-8

Upstream product

• 87357-65-1 (3R)-3-hydroxytetradecanoic acid phenacyl ester 
• 143465-64-9 (1S,2S,3R,4R,5R)-3,4-di-O-benzyl-2-benzylamino-5-C-hydroxymethyl-1,3,4-cyclohexanetriol 
• 143465-60-5 (R)-3-Benzyloxymethoxy-tetradecanoic acid (2R,4aR,6S,7R,8R,8aR)-7-((R)-3-benzyloxymethoxy-tetradecanoylamino)-6-(diphenoxy-phosphoryloxy)-2-phenyl-hexahydro-benzo[1,3]dioxin-8-yl ester 
• 143465-52-5 Phosphoric acid (1S,2R,3R,4R,5R)-3,4-bis-benzyloxy-5-benzyloxymethyl-2-((R)-3-methoxymethoxy-tetradecanoylamino)-cyclohexyl ester diphenyl ester 
• 143465-55-8 (R)-3-Methoxymethoxy-tetradecanoic acid (4aR,6S,7R,8R,8aR)-6-(diphenoxy-phosphoryloxy)-7-((R)-3-methoxymethoxy-tetradecanoylamino)-2,2-dimethyl-hexahydro-benzo[1,3]dioxin-8-yl ester 
• 143465-59-2 Phosphoric acid (2R,4aR,6S,7R,8R,8aR)-7-((R)-3-benzyloxymethoxy-tetradecanoylamino)-8-hydroxy-2-phenyl-hexahydro-benzo[1,3]dioxin-6-yl ester diphenyl ester 
• 143465-63-8 Phosphoric acid (1S,2R,3R,4R,5R)-2-benzylamino-3,4-bis-benzyloxy-5-benzyloxymethyl-cyclohexyl ester diphenyl ester 
• 143465-54-7 Phosphoric acid (4aR,6S,7R,8R,8aR)-8-hydroxy-7-((R)-3-methoxymethoxy-tetradecanoylamino)-2,2-dimethyl-hexahydro-benzo[1,3]dioxin-6-yl ester diphenyl ester 
• 143465-51-4 Phosphoric acid (1S,2R,3R,4R,5R)-2-amino-3,4-bis-benzyloxy-5-benzyloxymethyl-cyclohexyl ester diphenyl ester 
• 143465-53-6 Phosphoric acid (1S,2R,3R,4R,5R)-3,4-dihydroxy-5-hydroxymethyl-2-((R)-3-methoxymethoxy-tetradecanoylamino)-cyclohexyl ester diphenyl ester 
• 143465-49-0 (3aS,4R,5R,6R,7aS)-3-Benzyl-4,5-bis-benzyloxy-6-benzyloxymethyl-hexahydro-benzooxazol-2-one 
• 106265-18-3 benzyl benzyl((2R,3S)-2,3-bis(benzyloxy)-6-hydroxy-4-oxocyclohexyl)carbamate 
• 143465-65-0 (R)-3-Benzyloxymethoxy-tetradecanoic acid ((1S,2R,3R,4R,6S)-2,3,6-trihydroxy-4-hydroxymethyl-cyclohexyl)-amide 
• 106265-19-4 (1S,2S,3R,4R)-3,4-di-O-benzyl-2-benzylamino-1,2-N,O-carbonyl-5-methoxymethylene-1,3,4-cyclohexanetriol 

Relevant academic research and scientific papers

Synthesis of carbocyclic analogues of lipid X

Carbocyclic analogues of lipid X and nor-lipid X (1 and 2) are synthesized respectively from amino-inososes 3 and 16a, readily prepared from exocyclic olefins by Ferrier rearrangement.

Synthesis of the carbon pseudosugar analog of lipid X

A carbocyclic analog (2) with a deactivated pseudo-anomeric phosphate of the lipopolysaccharide biosynthetic intermediate Lipid X (1) was prepared in order to better understand the biological behavior of the parent compound. Two related synthetic routes t