1434876-00-2

Upstream product

• 145032-58-2 ethyl (1S,5R)-2-oxo-3-oxabicyclo[3.1.0]hexane-1-carboxylate 
• 1125-88-8 benzaldehyde dimethyl acetal 
• 144985-81-9 ethyl (1R,2R)-1,2-bis(hydroxymethyl)-1-cyclopropanecarboxylate 

Downstream Products

• 1434876-01-3 [(1S,7R)-4-phenyl-3,5-dioxabicyclo[5.1.0]octan-1-yl]methanol 
• 1434876-05-7 [(1R,7R)-4-phenyl-3,5-dioxabicyclo[5.1.0]octan-1-yl]methyl methanesulfonate 

Relevant academic research and scientific papers

METHOD FOR PREPARING CYCLOPROPANE DERIVATIVES

The present invention relates to the preparation of cyclopropane derivatives, in particular 2-amino-9-[[(1S,2R)-1,2-bis(hydroxymethyl)cyclopropyl]methyl]-4,8-dihydro-1H-purin-6-one, especially via the [(1S,7R)-4-phenyl-3,5-dioxabicyclo[5.1.0]octan-1-yl]methanol intermediate.

METHOD FOR PREPARING CYCLOPROPANE DERIVATIVES

The present invention relates to the preparation of cyclopropane derivatives, in particular 2- amino-9-[[(1S,2R)-1,2- bis(hydroxymethyl) cyclopropyl] methyl]-4,8-dihydro-1H-purin-6-one, especially via the [(1S,7R)-4-phenyl-3,5-dioxabicyclo[5.1.0]octan-1-yl]methanol intermediate.