145032-58-2 Usage
Uses
Used in Organic Synthesis:
3-Oxabicyclo[3.1.0]hexane-1-carboxylic acid, 2-oxo-, ethyl ester, (1S,5R)is used as a building block in organic synthesis for the preparation of various organic compounds. Its unique bicyclic structure and carbonyl group make it a valuable intermediate in the synthesis of complex organic molecules.
Used in Pharmaceutical Industry:
3-Oxabicyclo[3.1.0]hexane-1-carboxylic acid, 2-oxo-, ethyl ester, (1S,5R)is used as a key intermediate in the synthesis of pharmaceuticals. Its unique structural and stereochemical properties make it a promising candidate for the development of new drugs with improved efficacy and selectivity.
Used in Agrochemical Industry:
3-Oxabicyclo[3.1.0]hexane-1-carboxylic acid, 2-oxo-, ethyl ester, (1S,5R)is used as a building block in the synthesis of agrochemicals, such as pesticides and herbicides. Its unique properties allow for the development of novel agrochemicals with enhanced performance and selectivity.
Used in Material Science:
3-Oxabicyclo[3.1.0]hexane-1-carboxylic acid, 2-oxo-, ethyl ester, (1S,5R)has potential applications in the development of new materials and fine chemicals due to its unique structural and stereochemical properties. It can be used as a component in the synthesis of advanced materials with specific properties, such as high thermal stability or specific optical characteristics.
Check Digit Verification of cas no
The CAS Registry Mumber 145032-58-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,4,5,0,3 and 2 respectively; the second part has 2 digits, 5 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 145032-58:
(8*1)+(7*4)+(6*5)+(5*0)+(4*3)+(3*2)+(2*5)+(1*8)=102
102 % 10 = 2
So 145032-58-2 is a valid CAS Registry Number.
145032-58-2Relevant articles and documents
Lipase-catalyzed synthesis of a tri-substituted cyclopropyl chiral synthon: A practical method for preparation of chiral 1-alkoxycarbonyl-2-oxo- 3-oxabicyclo[3.1.0]hexane
Tsuji, Takashi,Onishi, Tomoyuku,Sakata, Katsutoshi
, p. 3819 - 3825 (1999)
An efficient method for the preparation of optically active enantiomers of 1-ethoxycarbonyl-2-oxo-3-oxabicyclo[3.1.0]hexane 1 has been developed. Treatment of 1 with lipase Amano PS gave (1S,5R)-1-carboxy-2-oxo-3- oxabicyclo[3.1.0]hexane 4a which was converted to (1S,5R)-1-ethoxycarbonyl-2- oxo-3-oxabicyclo[3.1.0]hexane 1a with high enantiomeric purity (98.0% ee, 75% yield), while the (1R,5S)-lactone ester 1b remained intact. A simple procedure for the recovery of 4a from the reaction mixture was also established.
Dimeric TADDOL Phosphoramidites in Asymmetric Catalysis: Domino Deracemization and Cyclopropanation of Sulfonium Ylides
Klimczyk, Sebastian,Misale, Antonio,Huang, Xueliang,Maulide, Nuno
, p. 10365 - 10369 (2015/09/01)
A gold-catalyzed asymmetric cyclopropanation of unactivated olefins with sulfonium ylides in the presence of a bimetallic catalyst with a novel dimeric TADDOL-phosphoramidite ligand is reported. This transformation allows a rare gold-catalyzed dynamic deracemization of chiral racemic substrates, where the same catalyst is responsible for several synergistic tasks in solution. The products are useful building blocks in synthesis and enable expeditious access to natural products.
