143539-91-7Relevant academic research and scientific papers
Regio- and stereoselective synthesis of isoxazolidine derivatives by asymmetric 1,3-dipolar cycloaddition reaction of chiral nitrones with 1-propene-1,3-sultone
Zhang, Hong-Kui,Chan, Wing-Hong,Lee, Albert W. M.,Wong, Wai-Yeung
, p. 957 - 962 (2008/12/20)
(Chemical Equation Presented) Asymmetric 1,3-dipolar cycloadditions of chiral nitrones to 1-propene-1,3-sultone (1) were investigated. Chiral nitrones 6a-e reacted with sultone 1 in toluene at 90°C for 24-36 h to give the corresponding isoxazolidines in m
Stereoselective aminohomologation of chiral α-alkoxy aldehydes via thiazole addition to nitrones. Application to the synthesis of N-acetyl-D-mannosamine
Dondoni,Junquera,Merchan,Merino,Tejero
, p. 4221 - 4224 (2007/10/02)
The addition of 2-lithiothiazole to nitrones derived from D-glyceraldehyde and D-arabinose affords anti-adducts from which α-amino aldehydes are revealed by thiazole-to-formyl deblocking. The methodology provides a new synthesis of N-acetyl D-mannosamine
